905712-38-1Relevant academic research and scientific papers
GLUCOSE SENSITIVE INSULIN DERIVATIVES
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Page/Page column 154, (2020/10/20)
The present invention relates to novel insulin derivatives and their use in the treatment or prevention of medical conditions relating to diabetes. The insulin derivatives are glucose sensitive and display glucose-sensitive albumin binding. The invention
GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES
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Page/Page column 120; 121; 159-161, (2019/05/30)
This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates. The diboron compounds are characterized by formula (I), which is: R1-X-R2, and wherein "X" is a mono- to multiatomic linker and where R1 and R2, which may be identical or different, each represents a group of Formula (lla) or (IIb) Also described are diboron conjugates represented by the general Formula (I'), which is: R1'-X'-R2', in which either the moeities R1' or R2' or X' carry a drug that is covalently attached to the diboron compound.
Solid-phase synthesis of m-phenylene ethynylene heterosequence oligomers
Elliott, Erin L.,Ray, Christian R.,Kraft, Stefan,Atkins, Joseph R.,Moore, Jeffrey S.
, p. 5282 - 5290 (2007/10/03)
Both homo- and heterosequence m-phenylene ethynylene oligomers are synthesized using a conceptually simple iterative solid-phase strategy. Oligomers are attached to Merrifield's resin through a known triazene-type linkage. The phenylene ethynylene molecul
