1229245-20-8

Basic information

• Product Name: 3-Bromo-5-iodo-4-methylbenzoic acid
• Synonyms: 3-Bromo-5-iodo-4-methylbenzoic acid
• CAS NO: 1229245-20-8
• Molecular Formula: C₈H₆BrIO₂
• Molecular Weight: 340.94051
• Product Categories: Acids & Esters;Bromine Compounds;Iodine Compounds
• Mol File: 1229245-20-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Bromo-5-iodo-4-methylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-5-iodo-4-methylbenzoic acid(1229245-20-8)
• EPA Substance Registry System: 3-Bromo-5-iodo-4-methylbenzoic acid(1229245-20-8)

Safety Data

• Hazardous Substances Data: 1229245-20-8(Hazardous Substances Data)

Upstream product

• 7697-26-9 3-bromo-4-methylbenzoic acid 

Downstream Products

• 1229245-19-5 3-bromo-5-(3-methoxyprop-1-yn-1-yl)-4-methylbenzoic acid 
• 1312350-29-0 (3R,4S)-N-[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl]-N-cyclopropyl-4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)-piperidine-3-carboxamide 
• 1194488-55-5 N-[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl]cyclopropanamine 
• 1312350-26-7 tert-butyl (3R,4S)-3-{[[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl](cyclopropyl)amino]carbonyl}-4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)piperidine-1-carboxylate 
• 1229245-18-4 3-bromo-N-cyclopropyl-5-(3-methoxyprop-1-yn-1-yl)-4-methylbenzamide 
• 1229245-21-9 3-bromo-N-cyclopropyl-5-(3-methoxypropyl)-4-methylbenzamide 
• 1194491-85-4 N-[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl]cyclopropanamine mesylate 
• 1312350-32-5 (3R,4S)-N-[3-bromo-5-(3-methoxypropyl)-4-methylbenzyl]-N-cyclopropyl-4-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)-piperidine-3-carboxamide hydrochloride 
• 1194488-76-0 3-{3-bromo-5-[(cyclopropylamino)methyl]-2-methylphenyl}-1-propanol 
• 1229244-86-3 methyl 3-bromo-5-formyl-4-methylbenzoate 
• 905712-38-1 methyl 3-bromo-5-iodo-4-methyl-benzoate 

Relevant articles and documents

GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES

This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates. The diboron compounds are characterized by formula (I), which is: R1-X-R2, and wherein "X" is a mono- to multiatomic linker and where R1 and R2, which may be identical or different, each represents a group of Formula (lla) or (IIb) Also described are diboron conjugates represented by the general Formula (I'), which is: R1'-X'-R2', in which either the moeities R1' or R2' or X' carry a drug that is covalently attached to the diboron compound.

3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS

The present invention relates to 3,4-substituted piperidinyl-based renin inhibitor compounds bearing at 4-position oxopyridine and having the formula (I). The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.