906477-25-6

Basic information

• Product Name: 2-(2-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]METHANOL
• Synonyms: 2-(2-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]METHANOL;[2-(2-Fluoro-phenyl)-1H-imidazol-4-yl]-methanol;2-(2-fluorophenyl)-1H-Imidazole-5-methanol;2-(2-Fluorophenyl)-1H-imidazole-4-methanol
• CAS NO: 906477-25-6
• Molecular Formula: C₁₀H₉FN₂O
• Molecular Weight: 192.1896632
• Mol File: 906477-25-6.mol

Chemical Properties

• Boiling Point: 438.415 °C at 760 mmHg
• Flash Point: 218.946 °C
• Appearance: /
• Density: 1.332 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.607
• Storage Temp.: 2-8°C
• PKA: 11.70±0.12(Predicted)
• CAS DataBase Reference: 2-(2-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]METHANOL(906477-25-6)
• EPA Substance Registry System: 2-(2-FLUOROPHENYL)-1H-IMIDAZOL-5-YL]METHANOL(906477-25-6)

Safety Data

• Hazardous Substances Data: 906477-25-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-Fluorophenyl)-1H-imidazol-5-yl]methanol is used as a building block for the synthesis of pharmaceutical compounds targeting specific biological pathways. Its unique structure allows for the development of drugs with potential therapeutic effects against various diseases and conditions.
Used in Organic Synthesis:
As a reagent, 2-(2-Fluorophenyl)-1H-imidazol-5-yl]methanol is employed in organic synthesis to facilitate the formation of complex organic molecules. Its presence in reactions can lead to the creation of new compounds with diverse applications in various industries.
Used in Analytical Chemistry:
2-(2-Fluorophenyl)-1H-imidazol-5-yl]methanol is utilized as a reference standard in analytical chemistry. Its consistent properties make it an ideal candidate for calibrating instruments and ensuring the accuracy of analytical measurements.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-(2-Fluorophenyl)-1H-imidazol-5-yl]methanol is used for the development of new drugs and therapeutic agents. Its unique chemical properties and potential for interaction with biological targets make it a valuable tool in the discovery and design of novel pharmaceuticals.

InChI:InChI=1/C10H9FN2O/c11-9-4-2-1-3-8(9)10-12-5-7(6-14)13-10/h1-5,14H,6H2,(H,12,13)

Upstream product

• 62147-49-3 1,3-dihydroxyacetone dimer 
• 57075-81-7 2-fluorobenzene-1-carboximidamide hydrogen chloride 
• 96-26-4 dihydroxyacetone 
• 394-47-8 2-fluorobenzonitrile 
• 71204-93-8 2-fluorobenzimidamide 

Downstream Products

• 1138033-98-3 2-(2-fluorophenyl)-1H-imidazole-4-carbaldehyde 
• 1027085-08-0 5-chloromethyl-2-(2-fluorophenyl)-1H-imidazole 

Relevant articles and documents

PYRROLOPYRIMIDINES AS CFTR POTENTIATORS

The present invention relates to compounds of Formula I, wherein R1a, R1b, R2, R3, R4, W, Y, and Z are as described herein, and pharmaceutically acceptable salts thereof. The compounds are potentiator

5-Membered heterocyclic compound

The present invention provides 5-membered heterocycle compounds represented by the following general formula (I): The present compounds have a superior acid secretion inhibitory effect, and shows an antiulcer activity and the like.

2-Phenyl-4-(aminomethyl)imidazoles as Potential Antipsychotic Agents. Synthesis and Dopamine D2 Receptor Binding

A series of 2-phenyl-4-(aminomethyl)imidazoles were designed as conformationally restricted analogs of the dopamine D2 selective benzamide antipsychotics.The title compounds were synthesized and tested for blockade of YM-09151 binding in cloned African green monkey dopamine D2 receptor preparations.The binding affinity data thus obtained were compared against that of the benzamides and a previously described series of 2-phenyl-5-(aminomethyl)pyrroles.