57075-81-7

Usage

Uses

Used in Chemical Research:
2-Fluorobenzamidine hydrochloride is used as a research intermediate for [its role in the synthesis of various organic compounds]. Its chemical structure, which includes a benzene ring, Fluorine atom, and hydrochloride group, makes it a valuable component in the development of new chemical entities.
Used in Organic Synthesis:
2-Fluorobenzamidine hydrochloride is used as a reagent in [the synthesis of complex organic molecules]. Its reactivity, due to the presence of the Fluorine atom and hydrochloride group, allows it to participate in various chemical reactions, contributing to the formation of desired products in organic synthesis processes.
Used in Pharmaceutical Industry:
2-Fluorobenzamidine hydrochloride is used as a building block in [the development of new pharmaceutical compounds]. Its potential to form hydrocarbon-related reactions and its reactivity make it a promising candidate for the creation of novel drug molecules.
Used in Material Science:
2-Fluorobenzamidine hydrochloride is used as a component in [the synthesis of advanced materials]. Its chemical properties and reactivity can be harnessed to create new materials with specific properties, such as improved stability or enhanced performance in various applications.

InChI:InChI=1/C7H7FN2.ClH/c8-6-4-2-1-3-5(6)7(9)10;/h1-4H,(H3,9,10);1H

Upstream product

• 394-47-8 2-fluorobenzonitrile 
• 4039-32-1 lithium hexamethyldisilazane 

Downstream Products

• 906477-25-6 [2-(2-fluorophenyl)-1H-imidazol-4-yl]methanol 
• 1027085-08-0 5-chloromethyl-2-(2-fluorophenyl)-1H-imidazole 
• 906477-25-6 (2-(2-fluorophenyl)-1H-imidazol-5-yl)methanol 
• 1569269-01-7 3,5-bis(2-fluorophenyl)-4H-1,2,4-triazole 
• 138426-25-2 5-chloro-3-(2-fluorophenyl)-1,2,4-thiadiazole 

Relevant academic research and scientific papers

TETRAHYDRO- AND DIHYDROQUINAZOLINONES

The present invention relates to the use of tetrahydro- and dihydroquinazolinones of formula (I) as protein kinase activators or inhibitors, a method for their manufacture, their use for the preparation of a medicament for the treatment of diseases, their

Access to variously substituted 5,6,7,8-tetrahydro-3H-quinazolin-4-ones via Diels-Alder adducts of phenyl vinyl sulfone to cyclobutene-annelated pyrimidinones

Under basic conditions (Et3N, dioxane), the aromatic amidines 4 and also S-methylisothiourea 4g cleanly undergo Michael addition to methyl 2-chloro-2-cyclopropylideneacetate (5), followed by intramolecular nucleophilic substitution, cyclopropyl

PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF

The invention relates to pyrimidine carboxylic acid derivatives of formula (I), to methods for the production thereof, to their use for treating and/or preventing diseases, and their use for producing medicaments for treating and/or preventing diseases, p

Triazole derivatives

The present invention relates to triazole and imidazole derivatives of formula I and to their pharmaceutically acceptable acid addition salts. These compounds are NMDA receptor subtype blockers and are useful for the treatment of diseases related to the NMDA receptor.

Preparation of Triazolopyrimidines as Potential Antiasthma Agents

With the use of the human basophil histamine release assay, 5-aryl-2-aminotriazolopyrimidines were found to be active as mediator release inhibitors.These compounds were prepared by reacting arylamidines with sodium ethyl formylacetate or with ethyl propiolate to give pyrimidinones.Treatment with phosphorus oxychloride gave a chloropyrimidine, which was converted to a hydrazinopyrimidine with hydrazine.Cyclization, using cyanogen bromide, gave the triazolopyrimidines, after a Dimroth rearrangement.Following a structure-activity evaluation, the5--2-amino (8-10), 5-(3-bromophenyl)-2-amino (8-13), 5--2-amino (8-11), and 5-(4-pyridinyl)-2-amino (6-7) compounds were found to have the best activity.They were chosen for further pharmacological and toxicological study.