57075-81-7

Basic information

• Product Name: 2-Fluorobenzamidine hydrochloride
• Synonyms: 2-FLUORO-BENZAMIDINE HCL;2-FLUORO-BENZAMIDINE HYDROCHLORIDE;BUTTPARK 74\03-61;2-fluorobenzimidamide hydrochloride;2-FLUOROBENZAMIDINE HYDROCHLORIDE, 95+%;2-Fluorobenzenecarboximidamide hydrochloride;2-FLUOROBENZAMIDINE HYDROCHLOR;1-(4-fluorophenyl)cyclopropane-1-carbonitrile
• CAS NO: 57075-81-7
• Molecular Formula: C₇H₇FN₂*ClH
• Molecular Weight: 174.6
• Product Categories: pharmacetical
• Mol File: 57075-81-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 98-100 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 211.4°C at 760 mmHg
• Flash Point: 81.6°C
• Appearance: /
• Vapor Pressure: 0.183mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-Fluorobenzamidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluorobenzamidine hydrochloride(57075-81-7)
• EPA Substance Registry System: 2-Fluorobenzamidine hydrochloride(57075-81-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 57075-81-7(Hazardous Substances Data)

Usage

General Description

2-Fluorobenzamidine hydrochloride is a chemical compound with the molecular formula C7H8FClN2. It is known for its role as an effective intermediate in chemical research and is commonly used in the field of organic synthesis. 2-Fluorobenzamidine hydrochloride's chemical structure includes a benzene ring, suggesting its potential to participate in hydrocarbon-related reactions. The presence of both the Fluorine atom and the hydrochloride group indicates this compound's potential for reactivity and its sizable role in chemical reactions. As with most chemicals, safe handling and proper storage of 2-Fluorobenzamidine hydrochloride are crucial to maintaining its stability and effectiveness. The compound is often stored in a cool, dry place to prevent any decomposition or unwanted reactions.

InChI:InChI=1/C7H7FN2.ClH/c8-6-4-2-1-3-5(6)7(9)10;/h1-4H,(H3,9,10);1H

Upstream product

• 394-47-8 2-fluorobenzonitrile 
• 4039-32-1 lithium hexamethyldisilazane 

Downstream Products

• 906477-25-6 (2-(2-fluorophenyl)-1H-imidazol-5-yl)methanol 
• 1027085-08-0 5-chloromethyl-2-(2-fluorophenyl)-1H-imidazole 
• 1569269-01-7 3,5-bis(2-fluorophenyl)-4H-1,2,4-triazole 
• 138426-25-2 5-chloro-3-(2-fluorophenyl)-1,2,4-thiadiazole 

Relevant articles and documents

TETRAHYDRO- AND DIHYDROQUINAZOLINONES

The present invention relates to the use of tetrahydro- and dihydroquinazolinones of formula (I) as protein kinase activators or inhibitors, a method for their manufacture, their use for the preparation of a medicament for the treatment of diseases, their

PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF

The invention relates to pyrimidine carboxylic acid derivatives of formula (I), to methods for the production thereof, to their use for treating and/or preventing diseases, and their use for producing medicaments for treating and/or preventing diseases, p

Preparation of Triazolopyrimidines as Potential Antiasthma Agents

With the use of the human basophil histamine release assay, 5-aryl-2-aminotriazolopyrimidines were found to be active as mediator release inhibitors.These compounds were prepared by reacting arylamidines with sodium ethyl formylacetate or with ethyl propiolate to give pyrimidinones.Treatment with phosphorus oxychloride gave a chloropyrimidine, which was converted to a hydrazinopyrimidine with hydrazine.Cyclization, using cyanogen bromide, gave the triazolopyrimidines, after a Dimroth rearrangement.Following a structure-activity evaluation, the5--2-amino (8-10), 5-(3-bromophenyl)-2-amino (8-13), 5--2-amino (8-11), and 5-(4-pyridinyl)-2-amino (6-7) compounds were found to have the best activity.They were chosen for further pharmacological and toxicological study.