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910297-65-3

2-Chloro-acetic Acid [3-Chloro-2-[(2-chloroacetyl)amino]phenyl]Methyl Ester is an organic compound that serves as a crucial intermediate in the synthesis of Dasatinib (D193600) and its metabolites. 2-Chloro-acetic Acid [3-Chloro-2-[(2-chloroacetyl)aMino]phenyl]Methyl Ester plays a significant role in the development of pharmaceuticals for the treatment of various cancers and immune system disorders.

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  • 910297-65-3 Structure

  • Basic information

    1. Product Name: 2-Chloro-acetic Acid [3-Chloro-2-[(2-chloroacetyl)aMino]phenyl]Methyl Ester
    2. Synonyms: 2-Chloro-acetic Acid [3-Chloro-2-[(2-chloroacetyl)aMino]phenyl]Methyl Ester
    3. CAS NO:910297-65-3
    4. Molecular Formula: C11H10Cl3NO3
    5. Molecular Weight: 310.561
    6. EINECS: N/A
    7. Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
    8. Mol File: 910297-65-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: Dichloromethane, Ethyl Acetate, Methanol
    9. CAS DataBase Reference: 2-Chloro-acetic Acid [3-Chloro-2-[(2-chloroacetyl)aMino]phenyl]Methyl Ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-Chloro-acetic Acid [3-Chloro-2-[(2-chloroacetyl)aMino]phenyl]Methyl Ester(910297-65-3)
    11. EPA Substance Registry System: 2-Chloro-acetic Acid [3-Chloro-2-[(2-chloroacetyl)aMino]phenyl]Methyl Ester(910297-65-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 910297-65-3(Hazardous Substances Data)

910297-65-3 Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-acetic Acid [3-Chloro-2-[(2-chloroacetyl)amino]phenyl]Methyl Ester is used as an intermediate in the preparation of Dasatinib (D193600) for the treatment of cancers and immune diseases. It contributes to the development of effective therapeutic agents that target specific molecular pathways, leading to improved patient outcomes and better management of these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 910297-65-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,0,2,9 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 910297-65:
(8*9)+(7*1)+(6*0)+(5*2)+(4*9)+(3*7)+(2*6)+(1*5)=163
163 % 10 = 3
So 910297-65-3 is a valid CAS Registry Number.

910297-65-3Relevant articles and documents

PROCESS FOR PREPARING N-(2-CHLORO-6-METHYLPHENYL)-2-[[6-[4-(2-HYDROXYETHYL)-1-PIPERAZINYL]-2-METHYL-4-PYRIMIDINYL]AMINO] -5-THIAZOLECARBOXAMIDE AND RELATED METABOLITES THEREOF

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Page/Page column 24; 25, (2010/11/28)

The present invention is directed to process for the preparation of metabolites as well as the parent compound of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl] amino]-5-thiazolecarboxamide, the compound of formula (I).

'N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamides metabolites

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Page/Page column 33, (2008/06/13)

The present invention is directed to metabolites of ′N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, the compound of formula (I), pharmaceutical compositions thereof, and to methods

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