91076-94-7

Basic information

• Product Name: ETHYL 3-AMINO-5-(4-CHLOROPHENYL)THIOPHE&
• Synonyms: ETHYL 3-AMINO-5-(4-CHLOROPHENYL)THIOPHE&;3-AMino-5-(4-chloro-phenyl)-thiophene-2-carboxylic acid ethyl ester
• CAS NO: 91076-94-7
• Molecular Formula: C₁₃H₁₂ClNO₂S
• Molecular Weight: 281.762
• Product Categories: Halogenated Heterocycles;Heterocyclic Building Blocks;Thiophenes;ThiophenesBuilding Blocks
• Mol File: 91076-94-7.mol

Chemical Properties

• Melting Point: 107-111 °C(lit.)
• Boiling Point: 472.8 °C at 760 mmHg
• Flash Point: 239.7 °C
• Appearance: Solid
• Density: 1.323 g/cm³
• Vapor Pressure: 4.16E-09mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: ETHYL 3-AMINO-5-(4-CHLOROPHENYL)THIOPHE&(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3-AMINO-5-(4-CHLOROPHENYL)THIOPHE&(91076-94-7)
• EPA Substance Registry System: ETHYL 3-AMINO-5-(4-CHLOROPHENYL)THIOPHE&(91076-94-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 91076-94-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL 3-AMINO-5-(4-CHLOROPHENYL)THIOPHE& is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a potential building block for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, ETHYL 3-AMINO-5-(4-CHLOROPHENYL)THIOPHE& is used as a precursor for the development of agrochemical products. Its chemical properties can be utilized to create new pesticides or herbicides with improved efficacy and selectivity.
It is important to handle and use ETHYL 3-AMINO-5-(4-CHLOROPHENYL)THIOPHE& with caution, as it may have harmful effects on human health and the environment if not properly managed.

InChI:InChI=1/C13H12ClNO2S/c1-2-17-13(16)12-10(15)7-11(18-12)8-3-5-9(14)6-4-8/h3-7H,2,15H2,1H3

Upstream product

• 78583-86-5 (E)-3-Chloro-3-(4-chloro-phenyl)-acrylonitrile 
• 105-36-2 ethyl bromoacetate 
• 4251-65-4 (4-chlorophenyl)acetaldehyde 
• 90272-22-3 2-chloro-3-(4-chlorophenyl)acrylonitrile 
• 623-51-8 ethyl 2-sulfanylacetate 

Downstream Products

• 1234799-82-6 2-amino-6-(4-chlorophenyl)thieno[3,2-d]pyrimidin-4(3H)-one 
• 187949-86-6 3-amino-5-(4-chlorophenyl)-2-thiophenecarboxylic acid 
• 91077-03-1 2-Ethoxycarbonyl-3-(4-dimethylaminophenylazo)-5-(4-chlorophenyl)-thiophene 
• 122945-82-8 2-(4-Chloro-phenyl)-7-methyl-9-oxo-9H-thiazolo[3,2-a]thieno[3,2-d]pyrimidine-6-carboxylic acid ethyl ester 

Relevant articles and documents

Synthesis of a series of novel thieno-and benzothieno[3,2-d]pyrimidin-4(3H) -ones

A series of novel thieno- and benzothieno[3,2-d]pyrimidin-4(3H)-ones is synthesised via condensation of 3-amino(benzo)thiophene-2-carboxylates with various lactams. Georg Thieme Verlag Stuttgart New York.

Synthesis of ethyl 3-amino-5-arylthiophene-2-carboxylates based on α-chlorocinnamonitriles

A new procedure was developed for preparation of ethyl 3-amino-5- arylthiophene-2-carboxylates by the reaction of α-chlorocinnamonitriles and their analogs with ethyl mercaptoacetate for a wide range of substrates. The reaction products form in high yield