918524-93-3

Basic information

• Product Name: 4-(benzyloxy)-2,6-difluorobenzaldehyde
• Synonyms: 4-(benzyloxy)-2,6-difluorobenzaldehyde;2,6-difluoro-4-(phenylmethoxy)Benzaldehyde
• CAS NO: 918524-93-3
• Molecular Formula: C14H10F2O2
• Molecular Weight: 248
• Mol File: 918524-93-3.mol

Chemical Properties

• Boiling Point: 338.9±37.0 °C(Predicted)
• Appearance: /
• Density: 1.278±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-(benzyloxy)-2,6-difluorobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzyloxy)-2,6-difluorobenzaldehyde(918524-93-3)
• EPA Substance Registry System: 4-(benzyloxy)-2,6-difluorobenzaldehyde(918524-93-3)

Safety Data

• Hazardous Substances Data: 918524-93-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-(benzyloxy)-2,6-difluorobenzaldehyde serves as a crucial building block in organic synthesis, particularly for the preparation of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 4-(benzyloxy)-2,6-difluorobenzaldehyde is utilized as a key intermediate in the synthesis of compounds with pesticidal or herbicidal properties, contributing to the advancement of crop protection agents.
Used in Material Science:
4-(benzyloxy)-2,6-difluorobenzaldehyde has been studied for its potential use in the development of novel materials. Its distinct chemical structure lends itself to the creation of innovative materials with specific properties for various applications.
Used as a Precursor in Specialty Chemicals Production:
Furthermore, 4-(benzyloxy)-2,6-difluorobenzaldehyde acts as a precursor in the production of specialty chemicals, where its reactivity and the presence of the benzyloxy and difluoro groups are exploited to synthesize high-value chemical products.

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 176175-97-6 1-benzyloxy-3,5-difluorobenzene 
• 532967-21-8 2,6-difluoro-4-hydroxybenzaldehyde 
• 100-39-0 benzyl bromide 

Relevant articles and documents

Highly Stereoselective Formation of a Spiro Center by a 1,4-Addition/Elimination Reaction of 3,5-Difluorocyclohexa-2,5-dienones

Spirocyclic 3,5-difluorocyclohexa-2,5-dienones possessing a triisopropylsiloxy-containing cyclic ether appendage were synthesized by oxidative dearomatization of the corresponding phenols. By group selectivity in the nucleophilic 1,4-addition/elimination reaction, highly stereoselective formation of the spiro center was successfully achieved. This reaction might provide access to total syntheses of (+)-bisdechlorogeodin and (+)-geodin with complete control of the formation of the spirocyclic structure.

ANTITUMOR EFFECT POTENTIATOR COMPRISING PYRROLOPYRIMIDINE COMPOUND

Disclosed is an antitumor effect potentiator for one or more other compounds having an antitumor effect, the antitumor effect potentiator comprising a novel pyrrolopyrimidine compound.

NOVEL PYRROLOPYRIMIDINE COMPOUND OR SALT THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAME, ESPECIALLY AGENT FOR PREVENTION AND/OR TREATMENT OF TUMORS ETC BASED ON NAE INHIBITORY EFFECT

An object to be solved by the present invention is to provide a novel pyrrolopyrimidine compound or a salt thereof having an NAE inhibitory action and a cell growth inhibitory effect. The present invention provides a compound or a salt thereof represented by Formula (A), as well as an NAE inhibitor, a pharmaceutical composition, and an antitumor agent comprising the compound or a salt thereof as an active ingredient.