91969-55-0

Basic information

• Product Name: 1,1-dimethylindan-4-ol
• Synonyms: 1,1-dimethylindan-4-ol;1,1-Dimethyl-4-indanol;2,3-Dihydro-1,1-dimethyl-1H-inden-4-ol;Einecs 295-247-6
• CAS NO: 91969-55-0
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.22826
• EINECS: 295-247-6
• Mol File: 91969-55-0.mol

Chemical Properties

• Boiling Point: 246.2°Cat760mmHg
• Flash Point: 110.8°C
• Appearance: /
• Density: 1.044g/cm³
• Vapor Pressure: 0.0176mmHg at 25°C
• Refractive Index: 1.551
• CAS DataBase Reference: 1,1-dimethylindan-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylindan-4-ol(91969-55-0)
• EPA Substance Registry System: 1,1-dimethylindan-4-ol(91969-55-0)

Safety Data

• Hazardous Substances Data: 91969-55-0(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Usage

Production of perfumes and fragrances

Aroma

Pleasant, sweet, and slightly floral odor

Industry

Fragrance industry

Additional uses

Cosmetic and personal care products

Application

Solvent

Application

Manufacturing of pharmaceuticals

Precursors

Synthesis of other organic compounds

Properties

Wide range of applications due to unique chemical properties and pleasant aroma

InChI:InChI=1/C11H14O/c1-11(2)7-6-8-9(11)4-3-5-10(8)12/h3-5,12H,6-7H2,1-2H3

Upstream product

• 79699-55-1 1,1-dimethyl-4-methoxyindan 
• 1128-92-3 2-prenylphenol 
• 71-43-2 benzene 
• 108-95-2 phenol 
• 110-82-7 cyclohexane 
• 5032-03-1 (3-methyl-butyl)-phenol 
• 110-83-8 cyclohexene 
• 870-63-3 prenyl bromide 
• 4957-17-9 1-methoxy-2-(3-methylbut-2-en-1-yl)benzene 
• 916488-93-2 7-chloro-1,1-dimethyl-4-methoxyindan 

Relevant articles and documents

Selective sp3 C-H bond activation based on a carbocation relay: Friedel-Crafts reaction with alkanes as the alkylating component

A highly efficient and selective intramolecular Friedel-Crafts reaction of 3-methylbutyl or 4-methylpentyl-substituted aromatics has been developed using a carbocation relay strategy through selective sp3 C-H bond activation, providing a facile and cost-effective approach for the construction of benzocyclic compounds. A variety of 1,1-dimethylindane and naphthalene derivatives have been prepared from very simple starting materials in good yields with high selectivity. The present strategy has provided a new example of a Friedel-Crafts reaction with alkanes as the alkylating component and constitutes a convenient approach to selective C-H bond activation and functionalization of alkane derivatives. A highly efficient and selective intramolecular Friedel-Crafts reaction of 3-methylbutyl or 4-methylpentyl- substituted aromatics has been developed using a carbocation relay strategy through selective sp3 C-H bond activation. The approach provides a facile and cost-effective route to benzocyclic compounds. Copyright

Synthesis of 1,1-dimethyl-4-indanol derivatives

The synthesis of 1,1-dimethyl-4-indanols (3a,b) has been achieved by intramolecular Friedel-Crafts cyclization of 2-(3-methyl-2-butenyl)phenols (5a,b) or 1-methoxy-2-(3-methyl-2-butenyl)benzenes (6a,b) followed by demethylation, respectively. It was found that the solvent was critical for the formation of different products in the intramolecular Friedel-Crafts reactions of 6. The unexpected product 4-methoxy-1,1,6,6-tetramethyl-as-hydrindacene (11) was obtained from the Friedel-Crafts reactions of 6a and its structure was confirmed by X-ray diffraction analysis. The key intermediates 5a,b were prepared by ortho-alkenylation of phenols with 1-bromo-3-methyl-2-butene, and the reaction temperature exerted an obvious impact on the yield of 2-(3-methyl-2-butenyl)phenol (5a). Copyright Taylor & Francis Group, LLC.