- Preparation method N- cyanoethyl - N - acetoxyethyl aniline
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The invention provides a preparation method of N - cyanoethyl - N - acetoxyethyl aniline. The preparation method comprises the following steps of 1) carrying out hydroxylation reaction N - cyanoethylaniline with ethylene oxide to obtain hydroxylate N - cyanoethyl - N - hydroxyethyl aniline. Step 2), the hydroxylate N - cyanoethyl - N - hydroxyethyl aniline is subjected to an esterification reaction with acetic anhydride and/or acetic acid to obtain an ester. N - Cyanoethyl - N - acetoxyethyl aniline prepared by the preparation method is low in cost and simple in step, and the obtained product is high in yield and high in purity.
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Paragraph 0060-0061; 0063-0064; 0066-0067; 0069-0070;...
(2021/09/29)
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- A method for utilizing the ion liquid preparation N - cyanoethyl - N - hydroxyethyl aniline
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The invention discloses a method for preparing N-cyanoethyl-N-ethoxylaniline by using an ionic liquid, belonging to the field of organic chemical synthesis. According to the method, aniline, chloroethanol and acrylonitrile used as raw materials are subjected to a one-pot process by using a high-heat-stability low-volatility recyclable ionic liquid as a catalyst and solvent to prepare the N-cyanoethyl-N-ethoxylaniline. The method does not use any toxic or harmful catalyst, is simple to operate, has the advantages of simple after-treatment, mild reaction conditions, favorable selectivity and high yield, and is a green novel method for efficiently synthesizing N-cyanoethyl-N-ethoxylaniline.
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Paragraph 0015; 0016; 0017; 0018; 0019; 0020; 0021-0034
(2017/06/02)
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- Synthetic technology of hydroxyethylaniline ester (III)
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The invention discloses a synthetic technology of hydroxyethylaniline ester (III). The synthesis process is shown by a chemical equation shown in the description. The technology has the following advantages: 1, the advantage of few instant reaction substances of a micro-channel reactor is used, so the flammable and explosive disadvantages of a hydroxyethylation reaction in a routine kettle are solved, the process safety is increased, and current chemical engineering safety operation requirements are met; and 2, the advantage of high mixing efficiency of the micro-channel reactor is used, the reaction can be carried out under solvent-free conditions when a hydroxyethylation reaction raw material is liquid, and when the excess amount of ethylene oxide is very small, so a reaction solution obtained after the hydroxyethylation reaction ends can be esterified in the micro-channel reactor, serial operation of two-step reactions is realized, and manpower and three wastes are greatly reduced. The technology is a new technology with simplified processes, and accords with environmental protection and safety requirements.
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Paragraph 0042; 0043; 0056; 0057; 0058
(2016/11/02)
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