cas 93273-63-3, Benzonitrile, 4-acetyl-2-bromo- | Articles data ｜lookchem

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93273-63-3

Articles about 93273-63-3Total 3 be found

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NOVEL AROMATIC COMPOUND AND USE THEREOF
Provided is a compound showing a bone formation promoting action (and/or bone resorption suppressive action). A compound of the formula (I) or a pharmacologically acceptable salt: [wherein each substituent is as defined in the DESCRIPTION], has low toxicity, shows good pharmacokinetics, has an action to promote bone formation, and is useful for the prophylaxis or To treatment of metabolic bone diseases (osteoporosis, fibrous osteitis (hyperparathyroidism), osteomalacia, Paget's disease that influences the systemic bone metabolism parameter etc.) associated with a decrease in the bone formation ability as compared to the bone resorption capacity.
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Paragraph 0647-0649

(2016/08/17)

MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY
The present invention relates to compounds of the formula (I). The compounds of the formula (I) are valuable pharmacologically active compounds. They exhibit a strong anti-thrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardio-vascular disorders like thromboembolic diseases or restenoses. They are inhibitors of the blood clotting enzymes, especially factor VIla and can in general be applied in conditions in which an undesired activity of factor VIla is present or for the cure or prevention of which an inhibition of factor VIla is intended. The invention furthermore relates to processes for the preparation of compounds of the formula (I), their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.
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(2009/03/07)

Nonsteroidal antiinflammatory agents. V. Photolysis of 6,11-dihydro-11-oxodibenz[b,e]oxepin-3-acetic acid
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Tagawa,Kubo
p. 3047 - 3052
(2007/10/02)

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Chemical Properties

Melting Point: 129-130 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling Point: 358.2±37.0 °C(Predicted)
Density: 1.56±0.1 g/cm3(Predicted)
PSA: 40.86000
LogP: 2.52338

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