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935292-72-1

Ethanone,1-(2-amino-5-iodo-3-methylphenyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

935292-72-1

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935292-72-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 935292-72-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,5,2,9 and 2 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 935292-72:
(8*9)+(7*3)+(6*5)+(5*2)+(4*9)+(3*2)+(2*7)+(1*2)=191
191 % 10 = 1
So 935292-72-1 is a valid CAS Registry Number.

935292-72-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-amino-5-iodo-3-methylphenyl)ethanone

1.2 Other means of identification

Product number -
Other names 1-(2-amino-5-iodo-3-methylphenyl)-1-ethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:935292-72-1 SDS

935292-72-1Relevant articles and documents

Addressing species specific metabolism and solubility issues in a quinoline series of oral PDE4 inhibitors

Lunniss,Eldred,Aston,Craven,Gohil,Judkins,Keeling,Ranshaw,Robinson,Shipley,Trivedi

scheme or table, p. 137 - 140 (2010/04/26)

Species specific conversion of the lead PDE4 inhibitor 1 to the quinolone 3 was identified as the major route of metabolism in the cynomolgus monkey. Modification of the template to give the cinnoline 9 retained potency and selectivity, and greatly improved the pharmacokinetic profile in the cynomolgus monkey compared with 1. Additional SAR studies aimed at improving the solubility of 9 are also described.

CINNOLINE COMPOUNDS AS INHIBITORS OF PHOSPHODIESTERASE TYPE IV (PDE4)

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Page/Page column 14; 70; 98-100, (2010/11/27)

There are provided according to the invention novel compounds of formula (I).

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