937600-99-2

Basic information

• Product Name: AKOS B030632
• Synonyms: AKOS B030632;4-[4-(Acetylamino)phenoxy]butanoic acid
• CAS NO: 937600-99-2
• Molecular Formula: C₁₂H₁₅NO₄
• Molecular Weight: 237.2518
• Mol File: 937600-99-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: AKOS B030632(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS B030632(937600-99-2)
• EPA Substance Registry System: AKOS B030632(937600-99-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 937600-99-2(Hazardous Substances Data)

Upstream product

• 1000774-76-4 ethyl 4-(4-N-acetylamino)phenoxybutyrate 
• 103-90-2 4-acetaminophenol 

Relevant articles and documents

Hapten, artificial antigens and antibody for detecting phenacetin as well as preparation method and application of hapten, artificial antigens and antibody

The invention provides a hapten, artificial antigens and an antibody for detecting phenacetin as well as a preparation method and application of the hapten, the artificial antigens and the antibody. A hapten 1, an artificial antigen 1 and an artificial antigen 2 are prepared, the artificial antigen 2 is used for preparing the specific antibody for detecting phenacetin, and the artificial antigen 1 is used as a coating antigen. The antibody has high-sensitivity and high-specificity recognition capability to phenacetin. The detection limit is 2ng/mL, and the cross reaction rate to structural analogues is lower than 3%. An immunoassay method of phenacetin is established, and the purpose of rapidly and accurately detecting phenacetin in herbal tea and other food is achieved.

Anti-Helicobacter pylori agents. 4. 2-(Substituted guanidino)-4-phenylthiazoles and some structurally rigid derivatives

In order to find a new class of anti-Helicobacter pylori (H. pylori) agents, a series of 4-[(3-acetamido)phenyl]-2-(substituted guanidino)thiazoles and some structurally rigid analoges were synthesized and evaluated for antimicrobial activity against H. pylori. Among the compounds obtained, high anti-H. pyrori activities were observed in benzyl derivative 34 (MIC = 0.025 μg/mL) and phenethyl derivatives 35 and 36 (MIC = 0.037 μg/mL and 0.017 μg/mL). Though alkyl derivatives generally showed lower activity, the 2-methoxyethyl derivative 28 preserved significant activity (MIC = 0.32 μg/mL) and also exhibited more potent gastric antisecretory activity than ranitidine. Structural restriction by bridging between the thiazole and the phenyl rings with an alkyl chain did not improve the activity in this series.