939775-62-9Relevant articles and documents
Development of a stereoselective and scalable process for the preparation of a methylcyclobutanol-pyridyl ether
Kuethe, Jeffrey T.,Basu, Kallol,Orr, Robert K.,Ashley, Eric,Poirier, Marc,Tan, Lushi
, p. 938 - 944 (2017/10/05)
The evolution of a scalable process for the preparation of methylcyclobutanol-pyridyl ether 1 is described. Key aspects of this development including careful control of the stereochemistry, elimination of chromatography, and application to kilogram-scale
ANTIBACTERIAL AGENTS
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, (2013/12/03)
Antibacterial compounds of formula (I) are provided, as well as stereoisomers and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.
6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR
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Page/Page column 97, (2015/05/06)
The invention relates to novel compounds of Formula I: wherein A, Y, R1, R2 and the subscript b each has the meaning as described herein and compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates, metabolites, isotopes, pharmaceutically acceptable salts, or prodrugs thereof. Compounds of Formula I and pharmaceutical compositions thereof are useful in the treatment of disease and disorders in which undesired or over-activation of NF-kB signaling is observed.
Cyclobutanone photoadducts of HCN and malononitrile: useful intermediates for the synthesis of C-nucleosides
Mladenova, Gabriela,Lee-Ruff, Edward
, p. 2787 - 2789 (2008/02/03)
Photochemistry of cyclobutanones in the presence of HCN or malononitrile give photoadducts derived from oxacarbene insertion into C-H. These intermediates are useful for the preparation of C-nucleosides by structural elaboration of the CN groups.