545882-60-8

Usage

Uses

Used in Organic Synthesis:
5,8-Dioxaspiro[3.4]octane-2-methanol is used as a building block in organic synthesis for its versatile reactivity, allowing for the creation of various complex organic molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, 5,8-Dioxaspiro[3.4]octane-2-methanol is utilized as a key intermediate in the synthesis of bioactive compounds, including natural products and drugs, due to its potential medicinal properties.
Used in the Development of New Materials:
5,8-Dioxaspiro[3.4]octane-2-methanol is studied for its potential applications in the development of new materials, leveraging its unique chemical structure and properties.
Used in Industrial Processes:
5,8-Dioxaspiro[3.4]octane-2-methanol is also considered for use in industrial processes, where its unique structure and reactivity could contribute to the advancement of chemical manufacturing techniques.

Upstream product

• 172324-66-2 3-(benzyloxymethyl)-2,2-dichlorocyclobutanone 
• 172324-67-3 3-benzyloxymethyl-cyclobutanone 
• 23761-23-1 3-oxocyclobutanecarboxylic acid 
• 695-95-4 methyl 3-oxocyclobutanecarboxylate 
• 198995-91-4 benzyl 3-oxocyclobutane-1-carboxylate 
• 545882-50-6 2-[(benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane 

Downstream Products

• 1057641-71-0 2-(bromomethyl)-5,8-dioxaspiro[3.4]octane 
• 183616-18-4 3-(hydroxymethyl)-cyclobutan-1-one 
• 939775-62-9 3-((tert-butyldimethylsilyl)oxy)methylcyclobutan-1-one 
• 172324-67-3 3-benzyloxymethyl-cyclobutanone 

Relevant academic research and scientific papers

PYRIDINE-1-OXIDE DERIVATIVES AND THEIR USE AS FACTOR XIA INHIBITORS

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.

Hydroxypurine compound and use thereof

The invention discloses a hydroxypurine compound and a use of the hydroxypurine compound as a PDE2 or TNFa inhibitor and concretely discloses a compound shown in the formula (I) and its tautomer or pharmaceutically acceptable salt.

SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND PHARMACEUTICAL USE OF SAME AS HIV INTEGRASE INHIBITOR

Provided is a substituted spiropyrido[1,2-a]pyrazine derivative or a pharmaceutically acceptable salt thereof, which is useful as an anti-HIV agent. The present invention relates to a compound represented by the following formula [I] or [II] or a pharmace

ANTIBACTERIAL AGENTS

Antibacterial compounds of formula (I) are provided, as well as stereoisomers and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.

PYRAZOLO (3, 4-B) PYRIDINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS

The present invention relates to phosphodiesterase (PDE) type 4, phosphodiesterase (PDE) type 7 and dual PDE type 4 /PDE type 7 inhibitors. Compounds disclosed herein having the structure of Formura 1: can be useful in the treatment, prevention, inhibitio

An efficient route to 3-substituted cyclobutanone derivatives

An efficient route to 3-(hydroxymethyl)cyclobutanone acetals via a [2+2] cycloaddition reaction is reported. The dramatic effect of different diol acetals on benzyl deprotection is discussed. Efficient synthesis of two synthetically useful intermediates, 3-methylenecyclobutanone acetal and 3-(bromomethyl)cyclobutanone, are provided.