943323-35-1Relevant articles and documents
A Novel Entry to 3,4,5-Trisubstituted 2-Pyrrolidones from Isoxazoline-N-oxides
Zhmurov, Petr A.,Ushakov, Pavel Yu.,Novikov, Roman A.,Sukhorukov, Alexey Yu.,Ioffe, Sema L.
supporting information, p. 1871 - 1874 (2018/08/28)
A novel strategy for the synthesis of stereochemically defined 3,4,5-trisubstituted 2-pyrrolidones was developed. The suggested approach involves reductive domino-type recyclization of 3-aminomethyl-substituted isoxazolines as a key stage. The latter are prepared via α-C-H functionalization of readily available isoxazoline-N-oxides.
METHOD OF PRODUCING PYRONE AND PYRIDONE DERIVATIVES
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Page/Page column 37, (2012/02/03)
The present invention provides a pyrone derivative and a pyridone derivative, which are novel intermediates for synthesizing an anti-influenza drug, a method of producing the same, and a method of using the same.
1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS
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Page/Page column 28, (2011/11/06)
The invention relates to 1,2-diamido-ethylene derivatives of the formula (I) wherein R1, R2, R3, and A are as described in the description and their use as medicaments, especially as orexin receptor antagonists.
1,2-DIAMIDO-ETHYLENE DERIVATIVES
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Page/Page column 62-63, (2009/04/25)
The invention relates to 1,2-diamido-ethylene derivatives of the formula (I) NHNR 3 OAOR 1 R 2 (I) wherein R1, R 2, R 3, and A are as described in the description and their use as medicaments, especially as orexin receptor
INHIBITORS OF AKT ACTIVITY
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Page/Page column 11; 35; 36, (2008/12/08)
Invented are novel heterocyclic carboxamide compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.
INHIBITORS OF AKT ACTIVITY
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Page/Page column 41, (2008/12/04)
Invented are novel pyrazole compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.