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944937-03-5

C16H18N2O2 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 944937-03-5 Structure

  • Basic information

    1. Product Name: C16H18N2O2
    2. Synonyms: C16H18N2O2
    3. CAS NO:944937-03-5
    4. Molecular Formula:
    5. Molecular Weight: 270.331
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 944937-03-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C16H18N2O2(CAS DataBase Reference)
    10. NIST Chemistry Reference: C16H18N2O2(944937-03-5)
    11. EPA Substance Registry System: C16H18N2O2(944937-03-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 944937-03-5(Hazardous Substances Data)

944937-03-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 944937-03-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,9,3 and 7 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 944937-03:
(8*9)+(7*4)+(6*4)+(5*9)+(4*3)+(3*7)+(2*0)+(1*3)=205
205 % 10 = 5
So 944937-03-5 is a valid CAS Registry Number.

944937-03-5Relevant articles and documents

Muscarinic receptor 1 agonist activity of novel N-aryl carboxamide substituted 3-morpholino arecoline derivatives in Alzheimer's presenile dementia models

Malviya, Manish,Sunil Kumar,Mythri,Venkateshappa,Subhash,Rangappa

experimental part, p. 5526 - 5534 (2009/12/06)

Earlier we have reported the effect of arecoline thiazolidinone and morpholino arecoline derivatives as muscarinic receptor 1 agonists in Alzheimer's presenile dementia models. To elucidate further our Structure-Activity Relationship (SAR) studies on the chemistry and muscarinic receptor 1 binding efficacy, a series of novel carboxamide derivatives of 2-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)morpholine molecule have been designed and synthesized as a new class of M1 receptor agonists with a low toxicity effect profile that enhances memory function in animal models of Alzheimer's presenile dementia and also modulates the APP secretion from rat brain cerebrocortical slices by activating M1 receptor in vitro. Results suggest that compound 9b having methyl group at the para position of the aryl group attached to the carboxamide of morpholino arecoline could emerge as a potent molecule having antidementia activity.

An efficient synthesis of 2-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)morpholine: a potent M1 selective muscarinic agonist

Sunil Kumar,Sadashiva,Rangappa

, p. 4565 - 4568 (2008/02/04)

2-(1-Methyl-1,2,5,6-tetrahydropyridin-3-yl)morpholine is useful for synthesizing potent antimicrobials including the arecoline derivatives, phendimetrazine and polygonapholine and was synthesised in nine steps with an overall yield of 36%. Bromination of

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