946053-90-3 Usage
Uses
Used in Pharmaceutical Industry:
(S)-4-Fluoro-indan-1-ylamine is utilized as a building block for the synthesis of various drug molecules and pharmaceutical intermediates. Its unique structure and chirality contribute to the development of new pharmaceuticals with specific therapeutic targets.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (S)-4-Fluoro-indan-1-ylamine serves as a key component in the design and synthesis of novel compounds with potential therapeutic applications. Its presence in drug molecules can influence pharmacokinetics, pharmacodynamics, and drug-target interactions.
Used in Drug Discovery:
(S)-4-FLUORO-INDAN-1-YLAMINE is employed in drug discovery processes to identify and optimize lead compounds with desired biological activities. Its unique structural features can be leveraged to enhance the potency, selectivity, and safety profiles of new drug candidates.
Used in Analytical Chemistry:
(S)-4-Fluoro-indan-1-ylamine is used as a reference compound in analytical chemistry. It aids in the development and validation of analytical methods, ensuring accurate and reliable measurements in chemical analyses.
Used in Chemical and Biological Studies:
As a research tool, (S)-4-Fluoro-indan-1-ylamine contributes to the understanding of chemical and biological processes. It can be used to probe the mechanisms of action, evaluate the binding affinities of drug molecules, and study the interactions between biological macromolecules and small organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 946053-90-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,6,0,5 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 946053-90:
(8*9)+(7*4)+(6*6)+(5*0)+(4*5)+(3*3)+(2*9)+(1*0)=183
183 % 10 = 3
So 946053-90-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H10FN/c10-8-3-1-2-7-6(8)4-5-9(7)11/h1-3,9H,4-5,11H2/t9-/m0/s1
946053-90-3Relevant articles and documents
NOVEL COMPOUNDS
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Page/Page column 56, (2022/03/22)
The invention relates to compounds of formula (I) and related aspects.
Mapping the substrate scope of monoamine oxidase (MAO-N) as a synthetic tool for the enantioselective synthesis of chiral amines
Herter, Susanne,Medina, Florian,Wagschal, Simon,Benha?m, Cyril,Leipold, Friedemann,Turner, Nicholas J.
, p. 1338 - 1346 (2017/10/06)
A library of 132 racemic chiral amines (α-substituted methylbenzylamines, benzhydrylamines, 1,2,3,4-tetrahydronaphthylamines (THNs), indanylamines, allylic and homoallylic amines, propargyl amines) was screened against the most versatile monoamine oxidase (MAO-N) variants D5, D9 and D11. MAO-N D9 exhibited the highest activity for most substrates and was applied to the deracemisation of a comprehensive set of selected primary amines. In all cases, excellent enantioselectivity was achieved (e.e. >99%) with moderate to good yields (55–80%). Conditions for the deracemisation of primary amines using a MAO-N/borane system were further optimised using THN as a template addressing substrate load, nature of the enzyme preparation, buffer systems, borane sources, and organic co-solvents.
SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS
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Page/Page column 19, (2008/12/04)
Therapeutic compounds, and methods, compositions, and medicaments related thereto are disclosed herein.
THERAPEUTIC FLUOROETHYLCYANO GUANIDINES
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Page/Page column 14, (2008/12/04)
Disclosed herein is compound having a formula as described herein. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
Monofluorinated derivatives of N-propargyl-1-aminoindan and their use as inhibitors of monoamine oxidase
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, (2008/06/13)
N-propargyl-1-amonoindan monofluorinated in the phenyl ring and their use as selective inhibitors of monoamine oxidase (MAO). There are provided several processes for the preparation of these novel compounds. There are also provided as novel compounds
