947590-61-6

Basic information

• Product Name: Benzeneacetic acid, 4-chloro-a-[[2-[[[(1,1-dimethylethoxy)carbonyl]amino]iminomethyl]benzo[b]thien-6-yl]oxy]-, methyl ester
• Synonyms: Benzeneacetic acid, 4-chloro-a-[[2-[[[(1,1-dimethylethoxy)carbonyl]amino]iminomethyl]benzo[b]thien-6-yl]oxy]-, methyl ester;LSKMKBUMZHWZKG-DHRITJCHSA-N
• CAS NO: 947590-61-6
• Molecular Formula: C₂₃H₂₃ClN₂O₅S
• Molecular Weight: 0
• Mol File: 947590-61-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzeneacetic acid, 4-chloro-a-[[2-[[[(1,1-dimethylethoxy)carbonyl]amino]iminomethyl]benzo[b]thien-6-yl]oxy]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 4-chloro-a-[[2-[[[(1,1-dimethylethoxy)carbonyl]amino]iminomethyl]benzo[b]thien-6-yl]oxy]-, methyl ester(947590-61-6)
• EPA Substance Registry System: Benzeneacetic acid, 4-chloro-a-[[2-[[[(1,1-dimethylethoxy)carbonyl]amino]iminomethyl]benzo[b]thien-6-yl]oxy]-, methyl ester(947590-61-6)

Safety Data

• Hazardous Substances Data: 947590-61-6(Hazardous Substances Data)

Upstream product

• 947590-65-0 N'-t-Boc-6-hydroxybenzothiophene-2-carboxamidine 
• 32174-34-8 methyl 4-chloromandelate 

Downstream Products

• 1209467-11-7 (2-carbamimidoylbenzo[b]thiophen-6-yloxy)-2-(4-chlorophenyl)acetic acid methyl ester trifluoroacetate 

Relevant articles and documents

Studies of benzothiophene template as potent factor IXa (FIXa) inhibitors in thrombosis

FIXa is a serine protease enzyme involved in the intrinsic pathway of the coagulation cascade. The upstream intervention of the coagulation cascade in selectively inhibiting FIXa would leave hemostasia intact via the extrinsic pathway, leading to an optim

HETEROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIOVASCULAR DISEASE

Heterocyclic compounds of the formula (I) are provided: wherein ring A, ring B, R1, R2, R3, R4, Y, m, n and q are as defined herein. R1 is in particular amidino. The invention further provides particular benzothiophene compounds. Compounds of the invention may be useful as inhibitors of Factor IXa and in the therapy of cardiovascular conditions and diseases, e.g. thrombosis.