32174-34-8

Basic information

• Product Name: ethyl (2R)-(4-chlorophenyl)(hydroxy)ethanoate
• Synonyms: methyl (2R)-2-(4-chlorophenyl)-2-hydroxyacetate;Benzeneacetic acid, 4-chloro-α-hydroxy-, methyl ester, (αR)-
• CAS NO: 32174-34-8
• Molecular Formula: C₉H₉ClO₃
• Molecular Weight: 214.6455
• Mol File: 32174-34-8.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 320.325°C at 760 mmHg
• Flash Point: 147.527°C
• Density: 1.27g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.543
• PKA: 11.99±0.20(Predicted)
• CAS DataBase Reference: ethyl (2R)-(4-chlorophenyl)(hydroxy)ethanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2R)-(4-chlorophenyl)(hydroxy)ethanoate(32174-34-8)
• EPA Substance Registry System: ethyl (2R)-(4-chlorophenyl)(hydroxy)ethanoate(32174-34-8)

Safety Data

• Hazardous Substances Data: 32174-34-8(Hazardous Substances Data)

Upstream product

• 492-86-4 (R)-4-chloro-α-hydroxy-benzeneacetic acid 
• 7099-88-9 4-chlorophenylglyoxylic acid 
• 93961-29-6 methyl 2-(4-chlorophenyl)-2-diazoacetate 
• 99-91-2 para-chloroacetophenone 
• 67-56-1 methanol 
• 104-88-1 4-chlorobenzaldehyde 
• 108-05-4 vinyl acetate 
• 32174-34-8 methyl 4-chloromandelate 
• 13312-83-9 4-chloromandelonitrile 
• 37542-28-2 methyl (p-chlorphenyl)glyoxylate 
• 7138-34-3 p-chloromandelic acid 
• 186581-53-3 diazomethane 
• 52449-43-1 (4-chloro-phenyl)-acetic acid methyl ester 
• 1353044-28-6 (4-chlorophenyl)[dimethyl(phenyl)silyl]methanol 

Downstream Products

• 186025-92-3 methyl 4-chloro-α-(methanesulfonyloxy)phenylacetate 
• 1260146-56-2 1-hydroxy-1-(4-chlorophenyl)-3-phenylpropanone 
• 1260146-94-8 C₁₆H₂₆ClNO₃Si 
• 854676-79-2 1-hydroxy-1-(4-chlorophenyl)-3-phenylpropanone 
• 1260146-93-7 2-(4-chlorophenyl)-2-hydroxy-N-methoxy-N-methylacetamide 
• 1584127-67-2 (S)-(+)-methyl 2-acetoxy-2-(4-chlorophenyl)acetate 
• 4674-24-2 2-(4-chlorophenyl)-2-methoxyacetic acid 
• 114898-40-7 methyl 2-(acetylthio)-2-(4-chlorophenyl)acetate 
• 133692-27-0 methyl 2-(4-chlorophenyl)-2-mercaptoacetate 
• 114898-41-8 2-(4-chlorophenyl)-2-mercaptoacetic acid 
• 940952-44-3 4-(p-chlorophenyl)-1,3,2-oxathiazolylium-5-olate 
• 23953-39-1 (2R)-2-(4-chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]acetic acid 
• 13312-93-1 4-chloro-α-hydroxyphenylacetyl hydrazine 

Relevant articles and documents

Synthesis of substituted mandelic acid derivatives via enantioselective hydrogenation: Homogeneous versus heterogeneous catalysis

An extensive screening of both homogeneous and heterogeneous catalysts was carried out for the enantioselective hydrogenation of p-chlorophenylglyoxylic acid derivatives. For p-chlorophenylglyoxylic amides only homogeneous Rh-diphosphine complexes gave sa

1,3-mandelic acid thioether derivative containing '4 - R/S - oxadiazole' structure and application thereof

1,3 Mandelic acid thioether compound containing the structure of '4 - R/S - oxadiazole' is characterized in that the structure is as shown in the general formula (In / IIn) and (In In-flight R1 A is H or Cl, R. 2 For linear alkanes C

New 4-aryl-1,3,2-oxathiazolylium-5-olates: Chemical synthesis and photochemical stability of a novel series of S-nitrosothiols

S-nitrosothiols (RSNOs) remain one of the most popular classes of NO-donating compounds due to their ability to release nitric oxide (NO) under non-enzymatic means whilst producing an inert disulphide by-product. However, alligning these compounds to the different biological fields of NO research has proved to be problematic due to the inherent instability of such compounds under a variety of conditions including heat, light and the presence of copper ions. 1,3,2-Oxathiazolylium-5-olates (OZOs) represent an interesting subclass of S-nitrosothiols that lock the –SNO moiety into a five membered heterocyclic ring in an attempt to improve the compound's overall stability. The synthesis of a novel series of halogen-containing OZOs was comprehensively studied resulting in a seven-step route and overall yields ranging between 21 and 37%. The photochemical stability of these compounds was assessed to determine if S-nitrosothiols locked within these mesoionic ring systems can offer greater stability and thereby release NO in a more controllable fashion than their non-cyclic counterparts.