950511-17-8

Basic information

• Product Name: 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine
• Synonyms: 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine;3-[3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,4-diaza-3-boratricyclo[7.3.1.0^{5,13}]trid;3-[3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,4-diaza-3-boratricyclo[7.3.1.0^{5,13}]trideca- 1(13),5,7,9,11-pentaene;(3-(1H-NAPHTHO[1,8-DE][1,3,2]DIAZABORININ-2(3H)-YL)PHENYL)BORONIC ACID PINACOL ESTER;m-Benzenediboronic Acid Pinacol Ester, 1,8-Diaminonaphthalene, Protected
• CAS NO: 950511-17-8
• Molecular Formula: C₂₂H₂₄B₂N₂O₂
• Molecular Weight: 370.07
• Mol File: 950511-17-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine(950511-17-8)
• EPA Substance Registry System: 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine(950511-17-8)

Safety Data

• Hazardous Substances Data: 950511-17-8(Hazardous Substances Data)

Usage

Chemical class

Boron-containing compounds

Core structure

Naphtho[1,8-de][1,3,2]diazaborinine

Ring system

2,3-dihydro-1H-naphtho

Substituent

2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]

Potential applications

Materials science, organic synthesis, and chemical research

Unique structure

Interesting target for further study and exploration

Relevance

Various fields of chemistry and related disciplines

Upstream product

• 927384-43-8 3-bromo-1-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)benzene 
• 73183-34-3 bis(pinacol)diborane 
• 1214264-88-6 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-naphtho[1,8-de][1,3,2]diazaborinine 
• 591-19-5 m-Bromoaniline 
• 89598-96-9 (3-bromophenyl)boronic acid 
• 479-27-6 naphthalene-1,8-diamine 

Downstream Products

• 1008097-01-5 3-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)-4'-methoxy-1,1'-biphenyl 
• 1008097-02-6 3-(2,3-dihydro-1H-naphtho[1,8-de]-1,3,2-diazaborinyl)-4'-acetyl-1,1'-biphenyl 
• 1614246-70-6 (3-(7-ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)benzene)boronic acid 
• 1614245-82-7 7-ethyl-4-[4'-(methylsulfonyl)biphenyl-3-yl]-7H-imidazo[4,5-c]pyridazine 

Relevant articles and documents

Direct transformation from arylamines to aryl naphthalene-1,8-diamino boronamides: A metal-free sandmeyer-type process

A direct metal-free transformation from arylamines to aryl naphthalene-1,8-diamino boronamides, a type of masked boronic acid, has been developed based on Sandmeyer-type reactions. A nonsymmetrical diboron reagent, B(pin)-B(dan), was utilized as the boryl

IMIDAZOPYRIDAZINE DERIVATIVES AS MODULATORS OF THE GABAA RECEPTOR ACTIVITY.

The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R and R6 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.

Chemical Compounds

The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.

Differentially protected benzenediboronic acids: Divalent cross-coupling modules for the efficient synthesis of boron-substituted oligoarenes

On the basis of the boron-masking strategy, new divalent cross-coupling modules have been designed for the efficient synthesis of boronsubstituted oligoarenes. The modules, i.e., monoprotected o-, m-, and p-benzenediboronic acid derivatives, undergo highly selective SuzukiMiyaura coupling with sp 2 iodides, bromides, chlorides, and triflates, affording coupling products in which the protected boronyl groups are left intact.