951885-14-6 Usage
Uses
Used in Pharmaceutical Research and Development:
N-butyl 5-bromopyridine-2-carboxamide is used as a building block for the synthesis of novel pharmaceutical compounds. Its unique chemical structure and potential biological activity make it a valuable starting material in the creation of new drugs.
Used in Medicinal Chemistry:
N-butyl 5-bromopyridine-2-carboxamide is used in medicinal chemistry for its potential to exhibit biological activity. Its unique chemical structure allows for the development of new drugs with specific therapeutic properties.
Used in Drug Discovery:
N-butyl 5-bromopyridine-2-carboxamide is used in drug discovery efforts due to its potential as a starting material for the creation of new drugs. Its unique chemical structure and potential biological activity make it an important chemical for scientific research and practical applications.
Used in Agrochemicals:
N-butyl 5-bromopyridine-2-carboxamide may have applications in the field of agrochemicals, where its unique chemical structure and potential biological activity can be utilized for the development of new agrochemical products.
Used in Material Science:
N-butyl 5-bromopyridine-2-carboxamide may also have applications in material science, where its unique chemical structure can be explored for the development of new materials with specific properties.
Check Digit Verification of cas no
The CAS Registry Mumber 951885-14-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,1,8,8 and 5 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 951885-14:
(8*9)+(7*5)+(6*1)+(5*8)+(4*8)+(3*5)+(2*1)+(1*4)=206
206 % 10 = 6
So 951885-14-6 is a valid CAS Registry Number.
951885-14-6Relevant articles and documents
Iridium(III)-Catalyzed Regioselective Intermolecular Unactivated Secondary Csp3?H Bond Amidation
Xiao, Xinsheng,Hou, Cheng,Zhang, Zhenhui,Ke, Zhuofeng,Lan, Jianyong,Jiang, Huanfeng,Zeng, Wei
, p. 11897 - 11901 (2016/11/16)
For the first time, a highly regioselective intermolecular sulfonylamidation unactivated secondary Csp3?H bond has been achieved using IrIIIcatalysts. The introduced N,N’-bichelating ligand plays a crucial role in enabling iridium–nitrene insertion into a secondary Csp3?H bond via an outer-sphere pathway. Mechanistic studies and density functional theory (DFT) calculations demonstrated that a two-electron concerted nitrene insertion was involved in this Csp3?H amidation process. This method tolerates a broad range of linear and branched-chain N-alkylamides, and provides efficient access to diverse γ-sulfonamido-substituted aliphatic amines.
Rh(III)-catalyzed cascade oxidative olefination/cyclization of picolinamides and alkenes via C-H activation
Cai, Shangjun,Chen, Chao,Shao, Peng,Xi, Chanjuan
, p. 3142 - 3145 (2014/06/23)
Rh(III)-catalyzed cascade oxidative alkenylation/cyclization of picolinamides and alkenes to furnish pyrido pyrrolone derivatives is described, in which three C-H bonds and one N-H bond broke, while one C-C bond and one C-N bond formed. The reaction proceeded with high yield and high regioselectivity and stereoselectivity. Moreover, copper acetate can also be used in catalytic amounts with O2 serving as the terminal oxidant.