100018-62-0Relevant articles and documents
New 1-amino-1,2-diphenylethanols as ligands for the enantioselective addition of alkyllithiums to benzaldehyde
Schoen, Michael,Naef, Reto
, p. 169 - 176 (2007/10/03)
In the presence of equimolar amounts of lithium alkoxides derived from N-substituted 2-amino-1,2-diphenylethanols, alkyllithium reagents add to benzaldehyde to furnish optically active secondary alcohols with enantiomeric excesses of up to 86%. The best results were obtained using the N-isopropyl- N-methyl substituted amino-alcohol.