10008-88-5

Basic information

• Product Name: Phenol, 4,4'-(1-methylethylidene)bis[2-[(diethylamino)methyl]-
• CAS NO: 10008-88-5
• Molecular Formula: C25H38N2O2
• Molecular Weight: 398.589
• Mol File: 10008-88-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phenol, 4,4'-(1-methylethylidene)bis[2-[(diethylamino)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4,4'-(1-methylethylidene)bis[2-[(diethylamino)methyl]-(10008-88-5)
• EPA Substance Registry System: Phenol, 4,4'-(1-methylethylidene)bis[2-[(diethylamino)methyl]-(10008-88-5)

Safety Data

• Hazardous Substances Data: 10008-88-5(Hazardous Substances Data)

Upstream product

• 80-05-7 BPA 
• 109-89-7 diethylamine 
• 74-95-3 1,1-dibromomethane 

Relevant articles and documents

Dibromomethane as one-carbon source in organic synthesis: The Mannich base formation from the reaction of phenolic compounds with a preheated mixture of dibromomethane and diethylamine

The salt formed from the reaction of dihalomomethane and diethylamine reacted with phenolic compounds to give the corresponding Mannich bases in modest to good yields. As for the relative rates and yields are in the following order: CH2Br2 > CH2Cl2. The CD2Cl2 is also applicable to prepare the deuterated analogues. At higher temperature, the elimination of diethylamine from Mannich base occurred to give the corresponding o-quinone methide intermediate, which was then trapped by another phenolic compound to give bis(2-hydroxy-1-aryl) methanes.