10011-97-9Relevant articles and documents
Development of a resonant-type microwave reactor and its application to the synthesis of positron emission tomography radiopharmaceuticals
Kimura, Hiroyuki,Yagi, Yusuke,Ohneda, Noriyuki,Odajima, Hiro,Ono, Masahiro,Saji, Hideo
, p. 680 - 686 (2014)
Microwave technology has been successfully applied to enhance the effectiveness of radiolabeling reactions. The use of a microwave as a source of heat energy can allow chemical reactions to proceed over much shorter reaction times and in higher yields tha
A simplified protocol for the automated production of succinimidyl 4-[ 18F]fluorobenzoate on an IBA Synthera module
Ackermann, Uwe,Yeoh, Shinn Dee,Sachinidis, John I.,Poniger, Stan S.,Scott, Andrew M.,Tochon-Danguy, Henri J.
, p. 671 - 673 (2011)
The important peptide labelling reagent succinimidyl 4-[ 18F]fluorobenzoate ([18F]SFB) has been synthesised in 75-85% decay corrected radiochemical yield using the IBA Synthera platform (IBA Cyclotron Solutions, Louvain-la-neuve, Bel
Preparation and evaluation of fluorine-18-labeled insulin as a molecular imaging probe for studying insulin receptor expression in tumors
Kim, Dong Hyun,Blacker, Megan,Valliant, John F.
, p. 3678 - 3686 (2014)
A convenient emulsion-based labeling method was used to synthesize fluorine-18-labeled insulin specifically B1-(4-[18F] fluorobenzoyl)insulin (18F-4b) in 6% overall radiochemical yield in 240 min. In vitro screening in MCF
Synthesis and in vitro evaluation of 18F- and 19F-labeled insulin: A new radiotracer for PET-based molecular imaging studies
Guenther, Katharina J.,Yoganathan, Sabesan,Garofalo, Robert,Kawabata, Thomas,Strack, Thomas,Labiris, Renée,Dolovich, Myrna,Chirakal, Raman,Valliant, John F.
, p. 1466 - 1474 (2006)
A new and regioselective strategy was developed for the preparation of fluorine-18-labeled insulin as a novel positron emission tomography (PET) tracer. [18F]-4-Fluorobenzoic acid (4-18FBA), which was produced in 83 ± 8% yield (n = 1
[18F]Ethenesulfonyl Fluoride as a Practical Radiofluoride Relay Reagent
Zhang, Bo,Fraser, Benjamin H.,Klenner, Mitchell A.,Chen, Zhen,Liang, Steven H.,Massi, Massimiliano,Robinson, Andrea J.,Pascali, Giancarlo
, p. 7613 - 7617 (2019)
Fluorine-18 is the most utilized radioisotope in positron emission tomography (PET), but the wide application of fluorine-18 radiopharmaceuticals is hindered by its challenging labelling conditions. As such, many potentially important radiotracers remain
Synthesis and liposome encapsulation of a novel 18F-conjugate of ω-conotoxin GVIA for the potential imaging of N-type Ca2+ channels in the brain by positron emission tomography
Azarian, Vahe,Gangloff, Anne,Seimbille, Yann,Delaloye, Sibylle,Czernin, Johannes,Phelps, Michael E.,Silverman, Daniel H. S.
, p. 269 - 283 (2006)
ω-Conotoxin GVIA is a potent, irreversible antagonist of N-type voltage gated Ca2+ channels. A radiofluorinated analogue of GVIA could be useful in assessing regional synaptic density of the brain, in vivo, using positron emission tomography. N
On-demand radiosynthesis of: N -succinimidyl-4-[18F]fluorobenzoate ([18F]SFB) on an electrowetting-on-dielectric microfluidic chip for 18F-labeling of protein
Kim, Hee-Kwon,Javed, Muhammad Rashed,Chen, Supin,Zettlitz, Kirstin A.,Collins, Jeffrey,Wu, Anna M.,Kim, Chang-Jin,Michael Van Dam,Keng, Pei Yuin
, p. 32175 - 32183 (2019)
An all-electronic, droplet-based batch microfluidic device, operated using the electrowetting on dielectric (EWOD) mechanism was developed for on-demand synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB), the most commonly
Identification, Characterization, and Optimization of Integrin αvβ6-Targeting Peptides from a One-Bead One-Compound (OBOC) Library: Towards the development of positron emission tomography (PET) imaging agents
Tang, Yng C.,Davis, Ryan A.,Ganguly, Tanushree,Sutcliffe, Julie L.
, (2019)
The current translation of peptides identified through the one-bead one-compound (OBOC) technology into positron emission tomography (PET) imaging agents is a slow process, with a major delay between ligand identification and subsequent lead optimization.
NOVEL MOLECULAR ASSEMBLY, MOLECULAR PROBE FOR MOLECULAR IMAGING AND MOLECULAR PROBE FOR DRUG DELIVERY SYSTEM USING THE SAME, AND MOLECULAR IMAGING SYSTEM AND DRUG DELIVERY SYSTEM
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Paragraph 0547-0550, (2019/04/25)
The present invention provides a molecular assembly which is less likely to accumulate in tissue other than cancer tissue, is highly safe for a living body, and can be prepared by a simple and safe method and whose particle size can be easily controlled.
