10020-43-6

Basic information

• Product Name: N-OCTYLMONOOXYETHYLENE
• Synonyms: 1-(2-Hydroxyethoxy)octane;Ethylene glycol mono-n-octyl ether;N-OCTYLMONOOXYETHYLENE;OCTYLGLYCOL;2-(OCTYLOXY)ETHANOL;C8C1;C8E1;ETHYLENE GLYCOL MONOOCTYL ETHER
• CAS NO: 10020-43-6
• Molecular Formula: C₁₀H₂₂O₂
• Molecular Weight: 174.28
• EINECS: 233-015-8
• Mol File: 10020-43-6.mol
• Article Data: 9

Chemical Properties

• Melting Point: -69.1°C (estimate)
• Boiling Point: 241℃
• Flash Point: 66℃
• Appearance: colorless or light yellow liquid
• Density: 0.880 g/mL at 20 °C(lit.)
• Vapor Pressure: 0.00608mmHg at 25°C
• Refractive Index: n20/D 1.436
• Storage Temp.: -20°C
• CAS DataBase Reference: N-OCTYLMONOOXYETHYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: N-OCTYLMONOOXYETHYLENE(10020-43-6)
• EPA Substance Registry System: N-OCTYLMONOOXYETHYLENE(10020-43-6)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R19:May form explosive peroxides.; R36/38:Irritating to eyes and skin.
• Safety Statements: S24/25:Avoid contact with skin and eyes.; S28A:After contact with skin, wash immediately with plenty of water.
• WGK Germany: 3
• F: 3
• Hazardous Substances Data: 10020-43-6(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid; odorless. Combustible.

Uses

Solvent for cellulose esters, plasticizers.

InChI:InChI=1/C10H22O2/c1-2-3-4-5-6-7-9-12-10-8-11/h11H,2-10H2,1H3

Upstream product

• 75-21-8 oxirane 
• 111-87-5 octanol 
• 107-21-1 ethylene glycol 
• 111-83-1 1-bromo-octane 
• 4359-57-3 2-heptyl-1,3-dioxolane 
• 93541-24-3 Aethylenglykol-octylaether-benzylaether 
• 1189171-78-5 1-methoxy-2-(2-octyloxy-ethoxy)-eth-1-yl-hydroperoxide 
• 96-49-1 [1,3]-dioxolan-2-one 

Downstream Products

• 53488-14-5 2-(octyloxy)acetaldehyde 
• 63632-58-6 2-(octyloxy)acetic acid 
• 93541-24-3 Aethylenglykol-octylaether-benzylaether 

Relevant articles and documents

Anchor dependency for non-glycerol based cationic lipofectins: Mixed bag of regular and anomalous transfection profiles

Although detailed structure-activity, physicochemical and biophysical investigations in probing the anchor influence in liposomal gene delivery have been reported for glycerol-based transfection lipids, the corresponding investigation for non-glycerol based simple monocationic transfection lipids have not yet been undertaken. Towards this end, herein, we delineate our structure-activity and physicochemical approach in deciphering the anchor dependency in liposomal gene delivery using fifteen new structural analogues (lipids 1-15) of recently reported non-glycerol based monocationic transfection lipids. The C14 analogues in both series 1 (lipids 1-6) and series 2 (lipids 7-15) showed maximum efficiency in transfecting COS-1 and CHO cells. However, the C12 analogue of the ether series (lipid 3) exhibited a seemingly anomalous behavior compared with its transfection efficient C10 and C14 analogues (lipids 2 and 4) in being completely inefficient to transfect both COS-1 and CHO cells. The present structure-activity investigation also convincingly demonstrates that enhancement of transfection efficiencies through incorporation of membrane re-organizing unsaturation elements in the hydrophobic anchor of cationic lipids is not universal but cell dependent. The strength of the interaction of lipids 1-15 with DNA was assessed by their ability to exclude ethidium bromide bound to the DNA. Cationic lipids with long hydrophobic tails were found, in general, to be efficient in excluding EtBr from DNA. Gel to liquid crystalline transition temperatures of the lipids was measured by fluorescence anisotropy measurement technique. In general (lipid 2 being an exception), transfection efficient lipids were found to have their mid transition temperatures at or below physiological temperatures (37°C).

METHOD FOR PRODUCING FAT ALCOHOL ETHOXYLATES

The invention relates to a process for preparing fatty alcohol ethoxylates. According to the invention, the fatty alcohol ethoxylates are not obtained by means of the reaction of the fatty alcohols with ethylene oxide, as known from the prior art, but rat

Highly efficient stereoselective catalytic C(sp3)-H insertions with donor rhodium carbenoids generated from cyclopropenes

Rings of five and six: Donor alkenyl rhodium carbenoids generated from 3,3-dimethylcyclopropenylcarbinols exhibit high reactivity in intramolecular C-H insertions. The reactions proceed under remarkably mild conditions, tolerate the presence of the free hydroxy group, and afford an efficient and stereoselective access to a variety of functionalized carbocycles and oxygen heterocycles. Copyright