1003011-06-0

Basic information

• Product Name: tert-butyl 2-(3-amino-1H-pyrazol-1-yl)acetate
• CAS NO: 1003011-06-0
• Molecular Weight: 197.237
• Mol File: 1003011-06-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl 2-(3-amino-1H-pyrazol-1-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(3-amino-1H-pyrazol-1-yl)acetate(1003011-06-0)
• EPA Substance Registry System: tert-butyl 2-(3-amino-1H-pyrazol-1-yl)acetate(1003011-06-0)

Safety Data

• Hazardous Substances Data: 1003011-06-0(Hazardous Substances Data)

Upstream product

• 1820-80-0 3-aminopyrazole 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 1364925-25-6 [3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-pyrazol-1-yl]-acetic acid tert-butyl ester 
• 1003011-05-9 (3-nitro-pyrazol-1-yl)-acetic acid tert-butyl ester 

Downstream Products

• 1364925-20-1 [3-(3-benzoyl-thioureido)-pyrazol-1-yl]-acetic acid tert-butyl ester 

Relevant articles and documents

METHODS OF TREATMENT WITH AMINOLEVULINIC ACID SYNTHASE 2 (ALAS2) MODULATORS

Described herein is a compound of Formula I or a pharmaceutically acceptable salt thereof: wherein Ring A R1, R2, a, b, and n are as defined herein. Also described is a method of treating a subject having a disorder in need of treatment, comprising inhibiting aminolevulinic acid synthase 2 (ALAS2) in the subject by administering a compound of Formula (I) or a pharmaceutically acceptable salt thereof. Disorders that are of particular interest are blood disorders, such as porphyria and anemia.

INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE

Compounds of formula (I) in free or salt form, wherein R1, R2, R3, and R4 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by mediated by phosphatidylinos