100422-91-1

Basic information

• Product Name: threo-1-(p-methylphenyl)-2-phenyl-2-phthalimidoethanol
• CAS NO: 100422-91-1
• Molecular Weight: 357.409
• Mol File: 100422-91-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: threo-1-(p-methylphenyl)-2-phenyl-2-phthalimidoethanol(CAS DataBase Reference)
• NIST Chemistry Reference: threo-1-(p-methylphenyl)-2-phenyl-2-phthalimidoethanol(100422-91-1)
• EPA Substance Registry System: threo-1-(p-methylphenyl)-2-phenyl-2-phthalimidoethanol(100422-91-1)

Safety Data

• Hazardous Substances Data: 100422-91-1(Hazardous Substances Data)

Upstream product

• 1074-82-4 potassium phtalimide 
• 17903-41-2 phenyl(trimethylsilyl)methyl bromide 
• 104-87-0 4-methyl-benzaldehyde 
• 100422-85-3 (α-phthalimidobenzyl)trimethylsilane 

Relevant articles and documents

Nucleophilic Aminomethylation of Aldehydes with α-Amino Alkylsilanes

Fluoride-induced desilylation of (α-phthalimido-, α-morpholino-, and α-acetamidobenzyl)silanes and a (phthalimidomethyl)silane generates the corresponding α-amino carbanions which add to a variety of aldehydes.The conversion of phthalimido group of the adducts into amino moiety leads to β-amino alcohols.This simple reaction sequence offers a new and general method of nucleophilic aminomethylation.