101-05-3

Basic information

• Product Name: ANILAZINE
• Synonyms: 4,6-dichloro-n-(2-chlorophenyl)-1,3,5-triazin-2-amine;5-triazin-2-amine,4,6-dichloro-n-(2-chlorophenyl)-3;Anilazin;Aniyaline;Bortrysan;Dairene;Dairin;Direz
• CAS NO: 101-05-3
• Molecular Formula: C₉H₅Cl₃N₄
• Molecular Weight: 275.52
• EINECS: 202-910-5
• Product Categories: Agro-Products;Aromatics;FUNGICIDE
• Mol File: 101-05-3.mol
• Article Data: 38

Chemical Properties

• Melting Point: 159-160℃
• Boiling Point: 425.99°C (rough estimate)
• Flash Point: 232.2 °C
• Appearance: white to light brown crystals or powder
• Density: 1.611
• Vapor Pressure: 1.17E-08mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• Storage Temp.: 0-6°C
• PKA: 0.43±0.10(Predicted)
• Water Solubility: 10mg/L(temperature not stated)
• Stability: Stable. Incompatible with oils and alkalies. May corrode some types of metal and alloy.
• Merck: 13,659
• BRN: 223133
• CAS DataBase Reference: ANILAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: ANILAZINE(101-05-3)
• EPA Substance Registry System: ANILAZINE(101-05-3)

Safety Data

• Hazard Codes: Xi,N
• Statements: 36/38-50/53
• Safety Statements: 22-60-61
• RIDADR: UN3077 9/PG 3
• WGK Germany: 3
• RTECS: XY7175000
• Hazardous Substances Data: 101-05-3(Hazardous Substances Data)

Usage

Chemical Properties

white to light brown crystals or powder

Uses

Different sources of media describe the Uses of 101-05-3 differently. You can refer to the following data:
1. Pesticide used to control fungus diseases in lawns and turf.
2. Fungicide.
3. Nonsystemic, foliar fungicide used in potatoes, tomatoes, wheat, barley and ornamentals.

Definition

ChEBI: A member of the class of triazenes that is dichlorotriazene in which the hydrogen is replaced by an o-chloroanilino group. A fungicide formerly used to control leaf spots and downy mildew, it is no longer approved for use within the European U ion.

General Description

White to tan crystals or white powder. Moderately soluble in organic solvents. Insoluble in water. Melting point 159°C.

Air & Water Reactions

Insoluble in water. Stable in neutral and slightly acidic aqueous media but hydrolyzes on heating with alkali.

Reactivity Profile

ANILAZINE is incompatible with oils and alkalis. ANILAZINE is slightly corrosive to metals.

Fire Hazard

Flash point data for ANILAZINE are not available; however, ANILAZINE is probably combustible.

Environmental Fate

Soil. Anilazine is readily degraded by soil bacteria (Harris et al., 1968). The reported half-life of anilazine in soil is approximately 12 hours (Hartley and Kidd, 1987)Plant. In plants, one or both of the chlorine atoms on the triazine ring may be replaced by thio or amino groups (Hartley and Kidd, 1987)Chemical/Physical. Anilazine is subject to hydrolysis (Windholz et al., 1983) releasing chlorine gas (Hartley and Kidd, 1987)

InChI:InChI=1/C9H5Cl3N4/c10-5-3-1-2-4-6(5)13-9-15-7(11)14-8(12)16-9/h1-4H,(H,13,14,15,16)

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 95-51-2 o-chloroaniline 
• 2451-62-9 teroxirone 
• 1137-42-4 4-Hydroxybenzophenone 
• 14221-01-3 tetrakis(triphenylphosphine) palladium⁽⁰⁾ 
• 108-86-1 bromobenzene 
• 497-19-8 sodium carbonate 
• 496879-77-7 2,7-dibromo-9-octyl-9H-fluorene 
• 2009-83-8 6-chloro-1-hexanol 
• 1668-53-7 2-(2,4-dihydroxyphenyl)-4,6-bis(2,4-dimethylphenyl)-1,3,5-triazine 
• 72510-64-6 1-[2-(2-chloroethoxy)ethoxy]hexane 
• 783-81-3 bis(3-aminophenyl)(methyl)phosphine oxide 
• 553-90-2 Dimethyl oxalate 
• 6938-68-7 2-methyl-thiosemicarbazide 

Downstream Products

• 27315-26-0 N-(2-chlorophenyl)-4,6-dimethoxy-1,3,5-triazine-2-amine 
• 524705-44-0 2-(2,4-dihydroxy-5-hexylphenyl)-4,6-bis(4-phenoxyphenyl)-1,3,5-triazine 
• 86386-73-4 fluconazole 
• 676360-50-2 4-[4-cycloheptylamino-6-(methyl-piperidin-4-yl-amino)-[1,3,5]triazin-2-ylamino]-phenol 
• 177605-92-4 2-Mesityl-4-(2-hydroxy-4-n-hexyloxy-phenyl)-6-[2-hydroxy-4-(11-hydroxy-undecyloxy)phenyl]-1,3,5-triazine 
• 129159-14-4 N-(2-Chloro-phenyl)-N'-(2-chloro-5-trifluoromethyl-phenyl)-N''-(4-nitro-phenyl)-[1,3,5]triazine-2,4,6-triamine 
• 129179-37-9 N-(2-Chloro-phenyl)-N'-(2-chloro-5-trifluoromethyl-phenyl)-N''-(2-nitro-phenyl)-[1,3,5]triazine-2,4,6-triamine 
• 129159-12-2 N-(2-Chloro-phenyl)-N'-(2-chloro-5-trifluoromethyl-phenyl)-N''-(2-ethoxy-phenyl)-[1,3,5]triazine-2,4,6-triamine 
• 129159-08-6 4-[4-(2-Chloro-phenylamino)-6-(2-chloro-5-trifluoromethyl-phenylamino)-[1,3,5]triazin-2-ylamino]-benzoic acid 
• 129159-09-7 3-[4-(2-Chloro-phenylamino)-6-(2-chloro-5-trifluoromethyl-phenylamino)-[1,3,5]triazin-2-ylamino]-benzoic acid 
• 129159-11-1 N-(2-Chloro-phenyl)-N'-(2-chloro-5-trifluoromethyl-phenyl)-N''-(2-methoxy-phenyl)-[1,3,5]triazine-2,4,6-triamine 
• 129159-15-5 N-(3-Chloro-phenyl)-N'-(2-chloro-phenyl)-N''-(2-chloro-5-trifluoromethyl-phenyl)-[1,3,5]triazine-2,4,6-triamine 
• 129159-10-0 3-[4-(2-Chloro-phenylamino)-6-(2-chloro-5-trifluoromethyl-phenylamino)-[1,3,5]triazin-2-ylamino]-phenol 
• 129159-13-3 N-(2-Chloro-phenyl)-N'-(2-chloro-5-trifluoromethyl-phenyl)-N''-m-tolyl-[1,3,5]triazine-2,4,6-triamine 

Related news

Normal coordinate analysis and fungicidal activity study on ANILAZINE (cas 101-05-3) and its related compound using spectroscopic techniques07/19/2019

The FTIR and FT-Raman spectra of anilazine have been recorded in the range 400–4000 cm−1 and 50–3500 cm−1 respectively. The optimized geometrical parameters of the compound were calculated using B3LYP method with 6-311G(d,p) basis set. The distribution of the vibrational bands were carried out...detailed

Relevant articles and documents

Design, synthesis, and cytotoxicity of novel 2,4,6-trisubstituted 1,3,5-triazines bearing aryl hydrazone moiety as potent antitumor agent

A novel series of 2,4,6-trisubstituted 1,3,5-triazine derivatives bearing aryl hydrazone moiety were designed and synthesized under the guidance of scaffold hopping and bioisosterism from the autophagy inhibitor VLX600. The target compounds were evaluated for cytotoxicity against HT-29 by MTT assay with VLX600 as positive control. Then, ten potent target compounds (5c-5f, 5i-5r, 5s, 5t) were further evaluated against two cancer cell lines H460 and A549 and one normal cell line WI-38. Most of them exhibited significant cytotoxicity against one or more cell lines. Particularly, a promising compound 5f was identified, which exhibited the most potent cytotoxicity against HT-29, H460 and A549 cancer cell lines with IC50 values of 0.047 μM, 0.071 μM and 0.071 μM, respectively, which was 10-to 62-folds more potent than VLX600 (IC50 = 0.47 μM, 4.1 μM, 4.4 μM). The preliminary structure-activity relationships (SARs) of the compounds were also discussed.

HEXAHYDROTRIAZINES, SYNTHESIS AND USE

Methods for making asymmetrical triazines are provided. The methods comprise first forming a mixture of at least two primary amines then reacting the mixture with an aldehyde. Methods for removing sulfides from hydrocarbon streams are also provided. The triazines may be added to the hydrocarbon stream in a molar ratio of triazine:H2S of about 10:1 to about 1:2.

N4-Phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-d iamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease

A series of 1,3,5-triazine-2,4,6-triamines were prepared and analyzed as inhibitors of glucocerebrosidase. Synthesis, structure activity relationships and the selectivity of chosen analogues against related sugar hydrolases enzymes are described.