10196-49-3

Basic information

• Product Name: 2,2,4-Trimethyl-1-oxa-4-aza-2-silacyclohexane
• Synonyms: 2,2,4-trimethyl-1-oxa-4-aza-2-silacyclohexane;2,2,4-Trimethyl-[1,4,2]Oxazasilinane;1-Oxa-4-aza-2-silacyclohexane, 2,2,4-trimethyl-;2,2,4-TRIMETHYL-1-OXA-4-AZA-2-SILACYCLOHEXANE/2,2,4-TRIMETHYL-1-OXA-4-AZA-2-SILICACYCLOHEXANE;2,2,4-trimethyl-2-silamorpholine;2,2,4-trimethyl-1-oxa-4-aza-2-silacycolhexane;2,2,4-Trimethyl-1-oxa-2-sila-4-azacyclohexane;2,2,4-Trimethyl-1-ox
• CAS NO: 10196-49-3
• Molecular Formula: C₆H₁₅NOSi
• Molecular Weight: 145.27
• EINECS: 233-487-5
• Mol File: 10196-49-3.mol

Chemical Properties

• Boiling Point: 141.1 °C at 760 mmHg
• Flash Point: 39.1 °C
• Appearance: /
• Density: 0.92 g/cm³
• Vapor Pressure: 5.94mmHg at 25°C
• Refractive Index: 1.446
• PKA: 7.94±0.20(Predicted)
• Water Solubility: 1000g/L
• CAS DataBase Reference: 2,2,4-Trimethyl-1-oxa-4-aza-2-silacyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,4-Trimethyl-1-oxa-4-aza-2-silacyclohexane(10196-49-3)
• EPA Substance Registry System: 2,2,4-Trimethyl-1-oxa-4-aza-2-silacyclohexane(10196-49-3)

Safety Data

• Hazard Codes: Xi
• RIDADR: 2920
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 10196-49-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,2,4-Trimethyl-1-oxa-4-aza-2-silacyclohexane is used as a precursor in the synthesis of pharmaceutical compounds for its ability to contribute to the development of new silicon-containing molecules with therapeutic properties.
Used in Materials Science:
In the field of materials science, 2,2,4-Trimethyl-1-oxa-4-aza-2-silacyclohexane is utilized as a component in the creation of organosilicon materials, which may exhibit unique properties beneficial for various applications, such as in coatings, adhesives, or sealants.
Used in Organic Chemistry:
2,2,4-Trimethyl-1-oxa-4-aza-2-silacyclohexane serves as a key intermediate in organic synthesis, allowing for the construction of complex organic molecules that can be further functionalized for specific uses in chemical research and development.

InChI:InChI=1/C6H15NOSi/c1-7-4-5-8-9(2,3)6-7/h4-6H2,1-3H3

Upstream product

• 109-83-1 (2-hydroxyethyl)(methyl)amine 
• 2351-13-5 1,3-bis(bromomethyl)-1,1,3,3-tetramethyldisiloxane 
• 18156-50-8 bromomethyl-ethoxy-dimethyl-silane 
• 141-43-5 ethanolamine 
• 1719-57-9 Chloro(chloromethyl)dimethylsilane 

Relevant articles and documents

Synthesis and conformational properties of substituted 1,4,2- oxazasilinanes: Low temperature NMR study and quantum chemical calculations

A number of N-substituted 2,2-dimethyl-1,4,2-oxazasilinanes 1 were synthesized and studied by variable temperature dynamic 1H and 13C NMR spectroscopy, room temperature 15N NMR spectroscopy and theoretical calculations at the DFT and MP2 levels of theory. Both the preferred conformers were assigned and the barrier to the ring inversion of the saturated six-membered ring determined. From 1 the corresponding methyl iodide salts were produced, their structure studied by X-ray analysis and found to be in excellent agreement with the results of the theoretical calculations.