105494-65-3

Basic information

• Product Name: TRI-N-BUTYL(1-PROPENYL)TIN
• Synonyms: 1-PROPENYLTRIBUTYLSTANNANE;1-PROPENYLTRIBUTYLTIN;2-METHYLVINYLTRIBUTYLTIN;TRI-N-BUTYL(1-PROPENYL)TIN;TRIBUTYL-1-PROPENYLTIN;1-Propenyltri-n-butylstannane~1-Propenyltri-n-butyltin~1-(Tri-n-butylstannyl)propene;2-Methylvinyltributyltin (cis/trans mixture);Tributyl-1-propenyltin (Z/E mixture)
• CAS NO: 105494-65-3
• Molecular Formula: C₁₅H₃₂Sn
• Molecular Weight: 331.12
• EINECS: -0
• Product Categories: Stannanes
• Mol File: 105494-65-3.mol

Chemical Properties

• Boiling Point: 90-92 °C (0.4 mmHg)
• Flash Point: 90-92°C/0.4mm
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.00087mmHg at 25°C
• Refractive Index: 1.4820
• Storage Temp.: Refrigerator (+4°C)
• BRN: 3935279
• CAS DataBase Reference: TRI-N-BUTYL(1-PROPENYL)TIN(CAS DataBase Reference)
• NIST Chemistry Reference: TRI-N-BUTYL(1-PROPENYL)TIN(105494-65-3)
• EPA Substance Registry System: TRI-N-BUTYL(1-PROPENYL)TIN(105494-65-3)

Safety Data

• Hazard Codes: N-T
• Statements: 50/53-48/23/25-36/38-25-21
• Safety Statements: 61-60-45-36/37/39-35
• RIDADR: 2788
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 105494-65-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
TRI-N-BUTYL(1-PROPENYL)TIN is used as a synthetic reagent for the production of Englerin A, a compound with potential therapeutic applications. It plays a crucial role in the synthesis process, enabling the creation of this bioactive molecule that may have significant implications in the development of new drugs and treatments.
Used in Chemical Synthesis:
In the field of organic chemistry, TRI-N-BUTYL(1-PROPENYL)TIN serves as a versatile reagent for various chemical reactions. Its unique properties allow it to facilitate the formation of new bonds and functional groups, contributing to the synthesis of a wide range of organic compounds with diverse applications in different industries.

InChI:InChI=1/3C4H9.C3H5.Sn/c3*1-3-4-2;1-3-2;/h3*1,3-4H2,2H3;1,3H,2H3;/rC15H32Sn/c1-5-9-13-16(12-8-4,14-10-6-2)15-11-7-3/h8,12H,5-7,9-11,13-15H2,1-4H3

Upstream product

• 590-14-7 1-bromo-1-propene 
• 1461-22-9 tributyltin chloride 
• 4226-01-1 tri-n-butyltin lithium 
• 74-86-2 acetylene 
• 917-54-4 methyllithium 
• 74-88-4 methyl iodide 
• 27262-82-4 tributylstannylmagnesium chloride 
• 123-38-6 propionaldehyde 
• 75-36-5 acetyl chloride 
• 937-63-3 p-Tolyl chlorothionoformate 
• 116064-59-6 1-tributylstannyl-propan-1-ol 

Downstream Products

• 91897-80-2 1-(1'-cyclohexenyl)-2-buten-1-one 
• 91897-81-3 (Z)-1-(cyclohexen-1-yl)-2-buten-1-one 
• 91897-73-3 (1E,4E)-1-phenyl-1,4-hexadien-3-one 
• 91897-74-4 (1E,4Z)-1-phenyl-1,4-hexadien-3-one 
• 91897-84-6 (E)-1-(5,5-dimethyl-1-oxo-cyclohex-2-en-3-yl)-2-buten-1-one 
• 120635-31-6 (7R,8R)-7-phenylacetamido-3-[(Z)-propen-1-yl]-3-cephem-4-carboxylic acid p-methoxybenzyl ester 
• 31552-03-1 (E)-pent-3-en-1-yn-1-ylbenzene 
• 31552-04-2 (Z)-1-phenyl-3-penten-1-yne 
• 1608-27-1 ((1E)-penta-1,3-dien-1-yl)benzene 
• 123-73-9 trans-Crotonaldehyde 
• 15798-64-8 cis-crotonaldehyde 
• 205056-69-5 (E)-methyl 2,4-dibenzyloxy-6-(1-propenyl)benzoate 
• 190790-85-3 (7R,8R)-7-phenylacetamido-3-[propen-1-yl]-3-cephem-4-carboxylic acid p-methoxybenzyl ester 

Relevant articles and documents

Ynamide Carbopalladation: A Flexible Route to Mono-, Bi- and Tricyclic Azacycles

Bromoenynamides represent precursors to a diversity of azacycles by a cascade sequence of carbopalladation followed by cross-coupling/electrocyclization, or reduction processes. Full details of our investigations into intramolecular ynamide carbopalladation are disclosed, which include the first examples of carbopalladation/cross-coupling reactions using potassium organotrifluoroborate salts; and an understanding of factors influencing the success of these processes, including ring size, and the nature of the coupling partner. Additional mechanistic observations are reported, such as the isolation of triene intermediates for electrocyclization. A variety of hetero-Diels-Alder reactions using the product heterocycles are also described, which provide insight into Diels-Alder regioselectivity.

Stannyl-cupration of Acetylenes and the Reaction of the Intermediate Cuprates with Electrophiles as a Synthesis of Substituted Vinylstannanes

Stannyl-cupration of acetylenes followed by electrophilic attack with a variety of electrophiles gives E-vinylstannanes.These can be used either to form acetylenes, thus achieving overall the addition of an ethynyl group, or to form carbon-carbon bonds in Stille reactions.

The Stannyl-Cupration of Acetylenes and the Reaction of the Intermediate Cuprates with Electrophiles as a Synthesis of Substituted Vinylstannanes

Stannyl-cupration of acetylenes followed by electrophilic attack with a variety of electrophiles gives vinylstannanes.

Process for production of ceophalosporins

Cephalosporin and 1-carba(1-dethia)cephalosporin antibiotics substituted in the 3-position with, inter alia, alkyl, alkenyl and alkynyl, are provided via process comprising conversion of a cephalosporin or 1-carba(1-dethia)-3-cephem substituted in the 3-p

THERMAL DECOMPOSITION OF ORGANOTIN SULFAMATES: A ONE POT SYNTHESIS OF VINYLTRIBUTYLTIN COMPOUNDS

The preparation of some alkyltributyltin sulfamates is described.Thermal decomposition of these compounds provides a route to vinyltributyltin derivatives.

Synthese et thermolyse eclair d'esters α-tributylstanniques

The preparation of some alkyltributyltin acetates and thiocarbonates is described.Flash thermolysis of these compounds at high temperature (600-950 deg C) and under a moderate vacuum, provides a new route to vinyltributyltin derivatives.