1080634-11-2Relevant articles and documents
Application of chiral cyclic nitrones to the diastereoselective synthesis of bicyclic isoxazolidine nucleoside analogues
Coutouli-Argyropoulou, Evdoxia,Xatzis, Christos,Argyropoulos, Nikolaos G.
, p. 84 - 100 (2008/09/18)
New bicyclic isoxazolidine nucleoside analogues are synthesized through 1,3-dipolar cycloaddition of enantiopure cyclic nitrones to appropriate vinyl nucleobases. The reactions are diastereoselective, giving as the main or the sole product the exo-Re cycloadducts. The diastereoselectivity depends on both the kind of the base and the substitution pattern of the nitrone. Copyright Taylor & Francis Group, LLC.