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3,5-Difluoro-4-hydroxyphenylboronic acid is a boronic acid derivative characterized by the molecular formula C6H5BFO3. It features a phenyl ring with two fluorine atoms at the 3rd and 5th positions and a hydroxyl group at the 4th position. 3,5-Difluoro-4-hydroxyphenylboronic acid is known for its versatile reactivity and potential biological activity, making it a valuable asset in various scientific fields.

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  • 1132666-81-9 Structure
  • Basic information

    1. Product Name: 3,5-Difluoro-4-hydroxyphenylboronic acid
    2. Synonyms: 3,5-Difluoro-4-hydroxyphenylboronic acid
    3. CAS NO:1132666-81-9
    4. Molecular Formula: C6H5BF2O3
    5. Molecular Weight: 173.9099064
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1132666-81-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 3,5-Difluoro-4-hydroxyphenylboronic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3,5-Difluoro-4-hydroxyphenylboronic acid(1132666-81-9)
    11. EPA Substance Registry System: 3,5-Difluoro-4-hydroxyphenylboronic acid(1132666-81-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1132666-81-9(Hazardous Substances Data)

1132666-81-9 Usage

Uses

Used in Organic Synthesis:
3,5-Difluoro-4-hydroxyphenylboronic acid is used as a reagent in organic synthesis for the formation of carbon-carbon and carbon-heteroatom bonds. Its unique structure allows for the creation of diverse molecular frameworks, facilitating the synthesis of complex organic compounds.
Used in Pharmaceutical Research and Drug Development:
In the pharmaceutical industry, 3,5-Difluoro-4-hydroxyphenylboronic acid serves as a building block for the synthesis of biologically active molecules. Its incorporation into drug candidates can potentially enhance their pharmacological properties, such as potency, selectivity, and bioavailability.
Used in Materials Science:
3,5-Difluoro-4-hydroxyphenylboronic acid has potential applications in materials science, where it can be utilized to develop novel materials with specific properties. Its unique chemical structure may contribute to the creation of materials with improved performance in various applications.
Used in Catalysis:
As a boronic acid derivative, 3,5-Difluoro-4-hydroxyphenylboronic acid can be employed as a catalyst or a catalyst precursor in various chemical reactions. Its ability to form stable intermediates and facilitate selective transformations makes it a promising candidate for catalytic applications.
Used in the Development of Fluorescent Probes for Biological Imaging:
3,5-Difluoro-4-hydroxyphenylboronic acid has potential use in the development of fluorescent probes for biological imaging. Its inherent fluorescence properties, combined with its reactivity, can be harnessed to create probes that selectively label and visualize specific biological targets, aiding in the study of cellular processes and disease mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 1132666-81-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,2,6,6 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1132666-81:
(9*1)+(8*1)+(7*3)+(6*2)+(5*6)+(4*6)+(3*6)+(2*8)+(1*1)=139
139 % 10 = 9
So 1132666-81-9 is a valid CAS Registry Number.

1132666-81-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (3,5-difluoro-4-hydroxyphenyl)boronic acid

1.2 Other means of identification

Product number -
Other names 3,5-Difluoro-4-hydroxyphenylboronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1132666-81-9 SDS

1132666-81-9Downstream Products

1132666-81-9Relevant articles and documents

Histone acetyltransferase P300 small molecule inhibitor and medicinal composition and application thereof

-

Paragraph 0082; 0087-0089, (2020/03/17)

The compound capable of inhibiting histone acetyltransferase, has a significant inhibition effect p300 in inhibiting the activity, of the histone acetyltransferase, or a pharmaceutically acceptable salt (I) of; has a significant inhibitory effect on tumor cells such as the primary, representative small molecule inhibitor p300 to prostate cancer cells, malignant blood tumor cells p300 breast cancer cells, and has an effect of inhibiting the toxicity C646, of the compound by overcoming the defects, of the original, small molecule inhibitor, existing in the present invention. C646 p300. The compounds of the formula C646; are shown in, Table (I). The invention belongs to, the field of pharmaceutical chemistry.

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