118869-56-0

Basic information

• Product Name: dimethyl N-<4-<<(2-amino-3-cyanopyrazin-5-yl)methyl>amino>benzoyl>-L-glutamate
• Synonyms: dimethyl N-<4-<<(2-amino-3-cyanopyrazin-5-yl)methyl>amino>benzoyl>-L-glutamate
• CAS NO: 118869-56-0
• Molecular Weight: 426.432
• Mol File: 118869-56-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl N-<4-<<(2-amino-3-cyanopyrazin-5-yl)methyl>amino>benzoyl>-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl N-<4-<<(2-amino-3-cyanopyrazin-5-yl)methyl>amino>benzoyl>-L-glutamate(118869-56-0)
• EPA Substance Registry System: dimethyl N-<4-<<(2-amino-3-cyanopyrazin-5-yl)methyl>amino>benzoyl>-L-glutamate(118869-56-0)

Safety Data

• Hazardous Substances Data: 118869-56-0(Hazardous Substances Data)

Upstream product

• 52407-60-0 dimethyl N-(4-amino-benzoyl)-L-glutamate 
• 40127-91-1 2-Amino-5-chloromethylpyrazine-3-carbonitrile 

Downstream Products

• 118869-51-5 N-<4-<<(4-aminopteridin-6-yl)methyl>amino>benzoyl>-L-glutamic acid 

Relevant articles and documents

Synthesis and biological activity of the 2-desamino and 2-desamino-2-methyl analogues of aminopterin and methotrexate

The previously undescribed 2-desamino and 2-desamino-2-methyl analogues of aminopterin (AMT) and methotrexate (MTX) were synthesized from 2-amino-5-(chloromethyl)pyrazine-3- carbonitrile. The AMT analogues were obtained via a three-step sequence consistin