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120493-42-7

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120493-42-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 120493-42-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,4,9 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 120493-42:
(8*1)+(7*2)+(6*0)+(5*4)+(4*9)+(3*3)+(2*4)+(1*2)=97
97 % 10 = 7
So 120493-42-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H22ClNO2/c1-10(2)13(17)14(18)19-15(3,4)9-11-5-7-12(16)8-6-11/h5-8,10,13H,9,17H2,1-4H3/t13-/m0/s1

120493-42-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name GEA 857

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120493-42-7 SDS

120493-42-7Downstream Products

120493-42-7Relevant articles and documents

New aralkyl esters and processes for their preparation

-

, (2008/06/13)

Compounds with the general formula I or pharmaceutically acceptable, salts thereof, wherein X and Y are halogen, CF3 or hydrogen, provided that both X and Y are not hydrogen and R is a straight or branched saturated or unsaturated alkyl group having 2-5 carbon atoms in the chain processes for the production of said compounds and the use of the said compounds for the treatment of mental disorders.

Inhibitors of neuronal monoamine uptake. II. Selective inhibition of 5-hydroxytryptamine uptake by α-amino acid esters of phenethyl alcohols

Lindberg,Thorberg,Bengtsson,Renyi,Ross,Ogren

, p. 448 - 456 (2007/10/06)

A series of α-amino acid esters of substituted phenethyl alcohols was prepared and tested as inhibitors of the neuronal reuptake of noradrenaline and 5-hydroxytryptamine. Some of the compounds are potent and very selective in blocking the 5-hydroxytryptamine uptake, as evidenced by biochemical data and behavioral tests. The most promising agent, alaproclate [2-(4-chlorophenyl)-1,1-dimethylethyl 2-aminopropanoate hydrochloride (1,IV), was selected for further studies as a potential antidepressant agent. A discussion on structure-activity relationships (SAR) is given. In an attempt to explain the selective action on the mechanism of 5-hydroxytryptamine uptake by the new inhibitors, their structures are compared with those of the two neurotransmitters. From the tentative pharmacophore and conformations of transmitter (5-HT) and inhibitor (alaproclate) derived from SAR, a hypothetic carrier site for 5-HT uptake is deduced in terms of geometry and electronic properties.

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