126991-59-1

Basic information

• Product Name: 8-(4-CHLORO-PHENYL)-1,4-DIOXA-SPIRO[4.5]DECAN-8-OL
• Synonyms: 8-(4-CHLORO-PHENYL)-1,4-DIOXA-SPIRO[4.5]DECAN-8-OL;4-(4-Chlorophenyl)-4-hydroxycyclohexan-1-one Ethylene Ketal
• CAS NO: 126991-59-1
• Molecular Formula: C₁₄H₁₇ClO₃
• Molecular Weight: 268.73598
• Product Categories: Aromatics;Heterocycles;Aromatics, Heterocycles
• Mol File: 126991-59-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 408.4°C at 760 mmHg
• Flash Point: 200.8°C
• Appearance: /
• Density: 1.3g/cm³
• Vapor Pressure: 2.11E-07mmHg at 25°C
• Refractive Index: 1.591
• Solubility: Chloroform, Dichloromethane
• CAS DataBase Reference: 8-(4-CHLORO-PHENYL)-1,4-DIOXA-SPIRO[4.5]DECAN-8-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(4-CHLORO-PHENYL)-1,4-DIOXA-SPIRO[4.5]DECAN-8-OL(126991-59-1)
• EPA Substance Registry System: 8-(4-CHLORO-PHENYL)-1,4-DIOXA-SPIRO[4.5]DECAN-8-OL(126991-59-1)

Safety Data

• Hazardous Substances Data: 126991-59-1(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

8-(4-Chlorophenyl)-1,4-dioxaspiro[4.5]decan-8-ol (cas# 126991-59-1) is a compound useful in organic synthesis.

InChI:InChI=1/C14H17ClO3/c15-12-3-1-11(2-4-12)13(16)5-7-14(8-6-13)17-9-10-18-14/h1-4,16H,5-10H2

Upstream product

• 4746-97-8 cyclohexanedione monoethylene ketal 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 106-39-8 bromochlorobenzene 
• 637-87-6 1-Chloro-4-iodobenzene 

Downstream Products

• 126991-60-4 4-(4-chlorophenyl)cyclohex-3-enone monoehtylene ketal 
• 1421369-93-8 4-(4-chlorophenyl)-1-(1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)cyclohexyl 2,2,2-trifluoroacetate 
• 1409956-67-7 cis/trans-2-(4-(4-chlorophenyl)cyclohexyl)-3,4-dihydronaphthalen-1(2H)-one 
• 1409956-62-2 2-(4-(4-chlorophenyl)cyclohex-1-en-1-yl)-3,4-dihydronaphthalen-1(2H)-one 
• 1203609-10-2 cis-2-[4-(4-chlorophenyl)cyclohexyl]-1,4-naphthoquinone 
• 1409957-04-5 trans-2-(4-(4-chlorophenyl)cyclohexyl)naphthalen-1-ol 
• 1409957-10-3 cis-2-(4-(4-chlorophenyl)cyclohexyl)naphthalen-1-ol 
• 1409956-99-5 cis/trans-2-(4-(4-chlorophenyl)cyclohexyl)naphthalen-1-ol 
• 1409956-88-2 trans-2-bromo-2-(4-(4-chlorophenyl)cyclohexyl)-3,4-dihydronaphthalen-1(2H)-one 
• 1409956-94-0 cis-2-bromo-2-(4-(4-chlorophenyl)cyclohexyl)-3,4-dihydronaphthalen-1(2H)-one 
• 1409956-84-8 cis/trans-2-bromo-2-(4-(4-chlorophenyl)cyclohexyl)-3,4-dihydronaphthalen-1(2H)-one 
• 1409956-73-5 trans-2-(4-(4-chlorophenyl)cyclohexyl)-3,4-dihydronaphthalen-1(2H)-one 
• 1409956-79-1 cis-2-(4-(4-chlorophenyl)cyclohexyl)-3,4-dihydronaphthalen-1(2H)-one 
• 1203609-11-3 cis/trans-(4-(4-chlorophenyl)cyclohexyl)naphthalen-1,4-dione 

Relevant articles and documents

Desymmetrizing Isomerization of Alkene via Thiazolinyl Iminoquinoline Cobalt Catalysis

We report a cobalt-catalyzed desymmetrizing isomerization of exo-cyclic alkenes to generate chiral 1-methylcyclohexene derivatives with good yields and enantioselectivities. A novel chiral thiazolinyl iminoquinoline ligand and its cobalt complex were desi

Visible Light Mediated Generation of trans-Arylcyclohexenes and Their Utilization in the Synthesis of Cyclic Bridged Ethers

While accessible via UV-irradiation of cis-cyclohexene, trans-cyclohexene has thus far been an investigation driven by curiosity, and due primarily to its short lifespan, has until recently not been employed for productive synthesis. Herein, we present st

Enantioselective Synthesis of Chiral Oxime Ethers: Desymmetrization and Dynamic Kinetic Resolution of Substituted Cyclohexanones

Axially chiral cyclohexylidene oxime ethers exhibit unique chirality because of the restricted rotation of C=N. The first catalytic enantioselective synthesis of novel axially chiral cyclohexylidene oximes has been developed by catalytic desymmetrization of 4-substituted cyclohexanones with O-arylhydroxylamines and is catalyzed by a chiral BINOL-derived strontium phosphate with excellent yields and good enantioselectivities. In addition, chiral BINOL-derived phosphoric acid catalyzed dynamic kinetic resolution of α-substituted cyclohexanones has been performed and yields versatile intermediates in high yields and enantioselectivities.