128094-95-1

Basic information

• Product Name: 1-(1-chloroethyl)-2-methoxybenzene
• Synonyms: 1-(1-chloroethyl)-2-methoxybenzene
• CAS NO: 128094-95-1
• Molecular Formula: C₉H₁₁ClO
• Molecular Weight: 170.64
• Mol File: 128094-95-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(1-chloroethyl)-2-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-chloroethyl)-2-methoxybenzene(128094-95-1)
• EPA Substance Registry System: 1-(1-chloroethyl)-2-methoxybenzene(128094-95-1)

Safety Data

• Hazardous Substances Data: 128094-95-1(Hazardous Substances Data)

Upstream product

• 13513-82-1 1-(2-methoxyphenyl)ethanol 
• 612-15-7 o-methoxystyrene 
• 41453-01-4 Methylniobtetrachlorid 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 461389-79-7 1-[1-(2-hydroxyphenyl)ethyl]piperidine 
• 612-15-7 o-methoxystyrene 

Relevant articles and documents

Metal-free regioselective hydrochlorination of unactivated alkenes via a combined acid catalytic system

A combined acid HCl/DMPU-acetic acid catalytic system was used in the hydrochlorination of a wide range of unactivated alkenes. This hydrochlorination strategy is remarkably greener than previous reported methods in terms of high atom efficiency, no toxic waste generated and metal-free process. The higher efficiency, compared with other commercially available HCl reagents, was augmented by the good regioselectivity and functionality tolerance found. A stepwise mechanism for this hydrochlorination process was proposed based on kinetic studies.

CHLORIERENDE METHYLIERUNG VON ALDEHYD- UND KETOGRUPPEN MIT NIOB-REAGENZIEN SOWIE AUFKLAERUNG DES MECHANISMUS

The reagents MeNbCl4 and Me2NbCl3, applied as isolated pure compounds, react with ketones in preparatively useful yields according to RR'CO -> RR'C(Cl)CH3.Whereas benzaldehyde reacts with MeNbCl4 analogously, the aliphatic aldehyde heptanal forms beside the expected product two cinechlorination products, indicating a mechanism via radicals.MeNbCl4 is highly aldehyde-vs.-ketone selective.Conversely, high ketone-vs.-aldehyde selectivity is achievable by application of MeNbCl4*PPh3 or NbCl5*PPh3 + 1.5 Me2Zn.