128832-35-9

Basic information

• Product Name: ETHYL 6-CHLORO-4-PHENYL-3-QUINOLINECARBOXYLATE
• Synonyms: ETHYL 6-CHLORO-4-PHENYL-3-QUINOLINECARBOXYLATE;ethyl 6-chloro-4-phenylquinoline-3-carboxylate
• CAS NO: 128832-35-9
• Molecular Formula: C₁₈H₁₄ClNO₂
• Molecular Weight: 311.76
• Mol File: 128832-35-9.mol

Chemical Properties

• Boiling Point: 452.9±45.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• PKA: 2.56±0.27(Predicted)
• CAS DataBase Reference: ETHYL 6-CHLORO-4-PHENYL-3-QUINOLINECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 6-CHLORO-4-PHENYL-3-QUINOLINECARBOXYLATE(128832-35-9)
• EPA Substance Registry System: ETHYL 6-CHLORO-4-PHENYL-3-QUINOLINECARBOXYLATE(128832-35-9)

Safety Data

• Hazardous Substances Data: 128832-35-9(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 623-47-2 propynoic acid ethyl ester 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 128832-34-8 diethyl <<(2-benzoyl-4-chlorophenyl)amino>methylene>malonate 

Downstream Products

• 128831-20-9 6-chloro-4-phenyl-3-quinolinecarboxylic acid 

Relevant articles and documents

Regioselective intramolecular annulations of ambident β-enamino esters: A diversity-oriented synthesis of nitrogen-containing privileged molecules

Diversity-oriented, regioselective, intramolecular annulation of β-enamino esters is described under solvent-free, calcium-catalysis. 2-aminoaryl ketones and alkyl propiolates undergone a [4+2] annulation to yield substituted quinolines; with an excess of

Investigation of prototypal MOFs consisting of polyhedral cages with accessible Lewis-acid sites for quinoline synthesis

A series of prototypal metal-organic frameworks (MOFs) consisting of polyhedral cages with accessible Lewis-acid sites, have been systematically investigated for Friedl?nder annulation reaction, a straightforward approach to synthesizing quinoline and its derivatives. Amongst them MMCF-2 demonstrates significantly enhanced catalytic activity compared with the benchmark MOFs, HKUST-1 and MOF-505, as a result of a high-density of accessible Cu(II) Lewis acid sites and large window size in the cuboctahedral cage-based nanoreactor of MMCF-2.

Novel Acyl-CoA:Cholesterol Acyltransferase Inhibitors. Synthesis and Biological Activity of 3-Quinolylurea Derivatives

A series of 3-quinolylurea derivatives (1) was synthesized and evaluated for acyl-CoA:cholesterol acyltransferase (ACAT) inhibitory activity.For in vitro studies, the most potent inhibitory activity was found in derivatives having substituents at the 6,7-

Quinoline derivatives, their production and use

Quinoline derivatives of the formula: STR1 , wherein R is hydrogen, alkyl or aralkyl; m and n are 0 or 1, and each of rings A, B and C can have substituents, which are useful as inhibitors for acyl-CoA:Cholesterolacyltransferase.