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4-BROMOBENZOFURAN is a light yellow oil that serves as a key intermediate in the synthesis of various organic compounds, particularly in the preparation of aminoalkylbenzofurans.

128868-60-0

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128868-60-0 Usage

Uses

Used in Pharmaceutical Industry:
4-BROMOBENZOFURAN is used as a chemical intermediate for the preparation of aminoalkylbenzofurans, which act as 5-HT2C agonists. These compounds have potential applications in the development of antiobesity and antidepressant medications, making them valuable in the pharmaceutical industry for addressing significant health concerns.

Check Digit Verification of cas no

The CAS Registry Mumber 128868-60-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,8,6 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 128868-60:
(8*1)+(7*2)+(6*8)+(5*8)+(4*6)+(3*8)+(2*6)+(1*0)=170
170 % 10 = 0
So 128868-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrO/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5H

128868-60-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Bromobenzofuran

1.2 Other means of identification

Product number -
Other names 4-bromo-1-benzofuran

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:128868-60-0 SDS

128868-60-0Relevant articles and documents

Bipolar fluorescent material based on benzoquinary heterocyclic ring and preparation method thereof and organic electroluminescent device

-

Paragraph 0071-0075, (2022/01/08)

The present invention discloses a bipolar fluorescent material based on a benzoquinary heterocyclic ring and a preparation method thereof with an organic electroluminescent device, the bipolar fluorescent material having the following structure shown: or

Five-membered heterocyclic oxo carboxylic acid compound and medical application thereof

-

, (2021/05/01)

The invention relates to a five-membered heterocyclic oxo carboxylic acid compound and a medical application thereof. Specifically, the invention relates to a compound, a pharmaceutical salt, a prodrug, a hydrate, a solvate or a crystal form as shown in a formula (I), and also relates to a preparation method of the compound, a pharmaceutical composition containing the compound and an application of the pharmaceutical composition as a secretion regulator of interferon type I, especially as an STING agonist in preparation of medicines for preventing and/or treating I-type interferon related diseases.

NAPHTHYRIDINE DERIVATIVES AS PRC2 INHIBITORS

-

Paragraph 0260-0261, (2020/11/03)

Disclosed are compounds of formula (I) or (II) that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.

IMIDAZO[1,2-C]PYRIMIDINE DERIVATIVES AS PRC2 INHIBITORS FOR TREATING CANCER

-

Paragraph 0175-0176, (2020/12/29)

Disclosed are compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, disclosed are compounds of Formula (I) and pharmaceutical compositions thereof, and methods of using the compounds and pharmaceutical compositions in, for example, methods of treating cancer.

Pyrimidine or pyrazino five-membered heterocyclic compound and applications thereof

-

, (2020/02/14)

The invention discloses a pyrimidine or pyrazino five-membered heterocyclic compound, a pharmaceutically acceptable salt, a hydrate, a prodrug, a stereoisomer or a solvate thereof, and provides a preparation method of the compound, a composition containing the compound, and applications of the compound in preparation of drugs for treating diseases or disorders related to the action mechanism of EED protein and/or PRC2 protein complex.

Dioxazolones as masked ester surrogates in the Pd(ii)-catalyzed direct C-H arylation of 6,5-fused heterocycles

Saxena, Paridhi,Maida, Neha,Kapur, Manmohan

supporting information, p. 11187 - 11190 (2019/09/30)

A simple and effective Pd(ii)-catalyzed regioselective C(2)-H arylation of 6,5-fused heterocycles with dioxazolones as a masked ester surrogate under mild conditions is reported. The significance of the arylation is highlighted by the new reactivity demonstrated in dioxazolones via proximal C-H activation of the cyclic carbonate of the hydroxamic acid functionality under protic conditions.

PRC2 INHIBITORS

-

Paragraph 0159; 0161-0162, (2019/08/26)

The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention. (Formula (I))

Pyrimidone compound and application thereof

-

, (2019/07/08)

The invention discloses a pyrimidone compound, pharmaceutically acceptable salt and solvate thereof, and provides a method for preparing the compounds, a composition containing the compounds and medicinal application of the compounds in preparation of medicines for treating diseases or disorders related to EED protein and/or PRC2 protein complex action mechanisms.

Pyrido/pyridazocyclic compound and application thereof

-

, (2019/12/25)

The invention discloses a pyrido/pyridazocyclic compound, a pharmaceutically acceptable salt and a solvent compound thereof. The invention further provides a preparation method of the compound, a composition with the compound and application of the compound for preparing medicines for treating diseases or disorders related to EED (embryonic ectoderm development) protein and/or PRC2 (polycomb repressive complex 2) protein composition action mechanisms.

PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS

-

, (2018/07/05)

Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.

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