1370190-85-4 Usage
Uses
Used in Pharmaceutical Industry:
(R)-1-((2-(2,4-difluorophenyl)-4-methylenetetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole is used as an antifungal agent for the treatment of various fungal infections. Its application is based on its ability to inhibit the synthesis of ergosterol, a vital component of the fungal cell membrane, which leads to the disruption of membrane integrity and the subsequent death of fungal cells.
Used in Agricultural Industry:
In addition to its pharmaceutical applications, (R)-1-((2-(2,4-difluorophenyl)-4-methylenetetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole also shows potential as a fungicide in the agricultural sector. It is utilized to protect crops from a wide range of fungal diseases, ensuring the health and productivity of the plants. (R)-1-((2-(2,4-difluorophenyl)-4-methylenetetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazole's effectiveness against various fungal pathogens makes it a valuable asset in crop protection and management.
Check Digit Verification of cas no
The CAS Registry Mumber 1370190-85-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,0,1,9 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1370190-85:
(9*1)+(8*3)+(7*7)+(6*0)+(5*1)+(4*9)+(3*0)+(2*8)+(1*5)=144
144 % 10 = 4
So 1370190-85-4 is a valid CAS Registry Number.
1370190-85-4Relevant articles and documents
Enantioselective synthesis of 2,2-disubstituted tetrahydrofurans: Palladium-catalyzed [3+2] cycloadditions of trimethylenemethane with ketones
Trost, Barry M.,Bringley, Dustin A.
, p. 4466 - 4469 (2013)
O rings: An approach to the title compounds has been developed utilizing a cycloaddition of trimethylenemethane with aryl ketones. The products are formed in up to a 96 % yield with 95 % ee. The reaction is catalyzed by palladium in the presence of L1, which possesses a stereogenic phosphorus atom, and only a single epimer at the phosphorus atom yields the active catalyst. Cp=cyclopentadiene, TMS=trimethylsilyl. Copyright
ANTIMYCOTIC TRIAZOLE COMPOUND
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Page/Page column 3; 13, (2017/07/08)
The invention relates to Compound (I), which is 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)-N-(4-fluorophenyl)benzamide, or a pharmaceutically acceptable salt thereof, usefu
ANTIMYCOTIC COMPOUND
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Page/Page column 16, (2016/06/28)
This invention relates to a compound, as defined in the specification, useful in the treatment of mycoses, compositions containing it and its use in therapy.