1401449-66-8

Basic information

• Product Name: N-cyclopropyl-2-methyl-4-{6-(pyridin-4-yl)-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}benzamide
• CAS NO: 1401449-66-8
• Molecular Weight: 479.505
• Mol File: 1401449-66-8.mol

Chemical Properties

• CAS DataBase Reference: N-cyclopropyl-2-methyl-4-{6-(pyridin-4-yl)-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclopropyl-2-methyl-4-{6-(pyridin-4-yl)-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}benzamide(1401449-66-8)
• EPA Substance Registry System: N-cyclopropyl-2-methyl-4-{6-(pyridin-4-yl)-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}benzamide(1401449-66-8)

Safety Data

• Hazardous Substances Data: 1401449-66-8(Hazardous Substances Data)

Upstream product

• 1401449-61-3 4-(4-amino-6-bromo-1H-benzimidazol-1-yl)-N-cyclopropyl-2-methylbenzamide 
• 1365243-78-2 [4-(cyclopropylcarbamoyl)-3-methylphenyl]boronic acid 
• 1401449-59-9 6-bromo-N-(3,3,3-trifluoropropyl)-1H-benzimidazol-4-amine 
• 1401449-58-8 tert-butyl 6-bromo-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazole-1-carboxylate 
• 1401449-57-7 tert-butyl 4-amino-6-bromo-1H-benzimidazole-1-carboxylate 
• 1360899-50-8 6-bromo-1H-1,3-benzodiazol-4-amine 
• 1121586-23-9 5-bromobenzene-1,2,3-triamine 
• 1351374-48-5 N-cyclopropyl-2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide 
• 62554-90-9 4-bromo-2,6-dinitroaniline 
• 345965-99-3 4-bromo-N-cyclopropyl-2-methylbenzamide 
• 68837-59-2 4-bromo-2-methylbenzoic acid 
• 606-22-4 2,6-dinitroaniline 

Relevant articles and documents

SUBSTITUTED BENZIMIDAZOLES

The present invention relates to substituted benzimidazole compounds of general formula (I) in which R3, R5 and A are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.