1422172-86-8

Basic information

• Product Name: (E)-2-(4-(2-cyclohexylvinyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• Synonyms: (E)-2-(4-(2-cyclohexylvinyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 1422172-86-8
• Molecular Weight: 312.26
• Mol File: 1422172-86-8.mol

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-(2-cyclohexylvinyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-(2-cyclohexylvinyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1422172-86-8)
• EPA Substance Registry System: (E)-2-(4-(2-cyclohexylvinyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane(1422172-86-8)

Safety Data

• Hazardous Substances Data: 1422172-86-8(Hazardous Substances Data)

Upstream product

• 870004-04-9 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)styrene 
• 695-12-5 vinylcyclohexane 
• 2156-04-9 4-Vinylphenylboronic acid 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 126812-30-4 1,3-dioxoisoindolin-2-yl cyclohexanecarboxylate 
• 98-89-5 Cyclohexanecarboxylic acid 

Downstream Products

• 1422172-95-9 2-(4-(2-cyclohexylethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

Irradiation-Induced Palladium-Catalyzed Decarboxylative Heck Reaction of Aliphatic N-(Acyloxy)phthalimides at Room Temperature

It is reported that Pd(PPh3)2Cl2 in combination with 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene (Xantphos) under irradiation of blue LEDs efficiently catalyzes a decarboxylative Heck reaction of vinyl arenes and vinyl heteroarenes with aliphatic N-(acyloxy)phthalimides at room temperature. A broad scope of secondary, tertiary, and quaternary carboxylates, including α-amino acid derived esters, can be applied as amenable substrates with high stereoselectivity. The experimental observation was explained by excitation-state reactivity of the palladium complex under irradiation to induce single-electron transfer to activate N-(acyloxy)phthalimides, and to suppress undesired β-hydride elimination of alkyl palladium intermediates.

Olefin cross-metathesis/Suzuki-Miyaura reactions on vinylphenylboronic acid pinacol esters

A series of alkenyl phenylboronic acid pinacol esters has been synthesized via an olefin cross-metathesis reaction of vinylphenylboronic acid pinacol ester derivatives. After catalytic hydrogenation, the resulting boronates were coupled via a microwave-mediated Suzuki-Miyaura reaction to afford a library of biarylethyl aryl and biarylethyl cycloalkyl derivatives. A complementary reaction sequence involved an initial Suzuki-Miyaura coupling.