143300-64-5

Basic information

• Product Name: 4-DIETHYLAMINO-PIPERIDINE
• Synonyms: AKOS BB-9179;4-DIETHYLAMINO-PIPERIDINE;DIETHYL-PIPERIDIN-4-YL-AMINE;4-DIETHYLAMINO-PIPERIDINE >98%;N,N-Diethyl-4-PiperidinaMine
• CAS NO: 143300-64-5
• Molecular Formula: C₉H₂₀N₂
• Molecular Weight: 156.27
• Product Categories: Amines and Anilines;Heterocycles;Piperidine
• Mol File: 143300-64-5.mol

Chemical Properties

• Boiling Point: 108°C/6mm
• Flash Point: 71.283 °C
• Appearance: /
• Density: 0.899 g/cm³
• Vapor Pressure: 0.16mmHg at 25°C
• Refractive Index: 1.478
• Storage Temp.: 2-8°C(protect from light)
• PKA: 10.32±0.20(Predicted)
• CAS DataBase Reference: 4-DIETHYLAMINO-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-DIETHYLAMINO-PIPERIDINE(143300-64-5)
• EPA Substance Registry System: 4-DIETHYLAMINO-PIPERIDINE(143300-64-5)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22
• Safety Statements: 23-24/25
• HazardClass: IRRITANT
• Hazardous Substances Data: 143300-64-5(Hazardous Substances Data)

Usage

Chemical Properties

Colorless to light yellow liquid

InChI:InChI=1/C9H20N2/c1-3-11(4-2)9-5-7-10-8-6-9/h9-10H,3-8H2,1-2H3

Upstream product

• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 109-89-7 diethylamine 
• 50534-25-3 4-(diethylamino)piperidine dihydrochloride 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 

Downstream Products

• 1197879-75-6 (E)-1-(4-Diethylamino-piperidin-1-yl)-3-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenyl]-propenone 
• 1422252-11-6 C₃₇H₄₃FN₄O₄ 
• 1370554-82-7 2-{[4-(diethylamino)piperidin-1-yl]methyl}-4,6-diiodophenol 

Relevant articles and documents

CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

An object of the present invention is to provide a compound exerting an analgesic effect against pain, in particular, neuropathic pain and/or fibromyalgia syndrome. The present invention provides a cyclic amine derivative represented by the following general formula, or a pharmacologically acceptable salt thereof.

CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF

A compound exerts a strong analgesic effect against pain, in particular, neuropathic pain and/or fibromyalgia syndrome. The cyclic amine derivative is represented by formula, a prodrug thereof or a pharmacologically acceptable salt thereof: wherein A represents a group represented by Formula (IIa), (IIb) or (IIc): wherein R3 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R4 represents a hydrogen atom or an alkylcarbonyl group having 2 to 6 carbon atoms or an alkyl group having 1 to 6 carbon atoms and optionally substituted with an alkylcarbonylamino group having 2 to 6 carbon atoms and n represents 1 or 2, in which when R3 and R4 each independently represent an alkyl group having 1 to 6 carbon atoms, R1 represents an alkyl group having 1 to 6 carbon atoms and substituted with a hydroxyl group, an amino group or a carboxyl group.

Cyclic amine derivative and pharmaceutical use thereof

The purpose of the present invention is to provide a compound that exerts a strong analgesic action against on pain, in particular, against neuropathic pain and/or fibromyalgia syndrome. The present invention provides a cyclic amine derivative represented by chemical formula, a prodrug thereof or a pharmaceutically acceptable salt thereof.

NOVEL FURANONE DERIVATIVE

To provide a novel furanone derivative, and a medicine including the same. The furanone derivative is represented by the formula (I): wherein A represents —COOR1 or a hydrogen atom; R1 represents a hydrogen atom, an optionally substituted hydrocarbon grou

Synthesis and biological studies of 1-amino β-carbolines

A selection of amino-substituted β-carbolines have been prepared and show anticancer and antimalarial activities. A selection of 1-amino-substituted β-carbolines have been prepared by amination of 1-chloro-β-carboline as simple mimics of manzamine A and chloroquine and their intercalating ability, anticancer and antimalarial activity were studied.