1440522-38-2Relevant articles and documents
Dual-functional abeo-taxane derivatives destabilizing microtubule equilibrium and inhibiting NF-κB activation
Zhao, Yu,Su, Jia,Goto, Masuo,Morris-Natschke, Susan L.,Li, Yan,Zhao, Qin-Shi,Yao, Zhu-Jun,Lee, Kuo-Hsiung
, p. 4749 - 4757 (2013/07/19)
Taxchinin A, with a 11(15→1)-abeo-taxane skeleton, is a major, but inactive taxoid contained in leaves of Taxus chinensis. In our design of dual-functional antitumor abeo-taxane derivatives, two fragments from antitumor agents with different molecular tar