144947-47-7

Basic information

• Product Name: 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE
• Synonyms: 1-(4-CHLOROBENZOYL)-4-PIPERIDONE;1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE;1-(4-Chlorobenzoyl)-4-Piperidinone
• CAS NO: 144947-47-7
• Molecular Formula: C₁₂H₁₂ClNO₂
• Molecular Weight: 237.68
• Mol File: 144947-47-7.mol

Chemical Properties

• Boiling Point: 417.7°Cat760mmHg
• Flash Point: 206.4°C
• Appearance: /
• Density: 1.298g/cm³
• Vapor Pressure: 3.48E-07mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE(144947-47-7)
• EPA Substance Registry System: 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE(144947-47-7)

Safety Data

• Hazardous Substances Data: 144947-47-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE is used as a key intermediate in the synthesis of a variety of pharmaceuticals for its ability to contribute to the development of drugs with diverse therapeutic applications.
Used in Antipsychotic Medications:
As a component in the production of antipsychotic drugs, 1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE aids in the management of psychotic disorders by modulating neurotransmitter activity in the brain.
Used in Antidepressant Formulations:
1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE is utilized in the creation of antidepressant medications, targeting the enhancement of mood and alleviation of depressive symptoms through its influence on neurochemical pathways.
Used in Analgesic Development:
1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE serves as a building block in the development of analgesics, contributing to the management of pain by interacting with pain perception and transmission mechanisms.
Used in Anti-inflammatory and Analgesic Research:
1-(4-CHLORO-BENZOYL)-PIPERIDIN-4-ONE is explored for its potential anti-inflammatory and analgesic effects, indicating its use in the advancement of treatments for inflammatory conditions and pain management.

InChI:InChI=1/C12H12ClNO2/c13-10-3-1-9(2-4-10)12(16)14-7-5-11(15)6-8-14/h1-4H,5-8H2

Upstream product

• 41979-39-9 4-piperidone hydrochloride 
• 122-01-0 4-chloro-benzoyl chloride 
• 40064-34-4 4-piperidone monohydrochloride monohydrate 

Downstream Products

• 156635-05-1 BIB₅₁₅ 
• 1036037-75-8 C₂₆H₃₁ClN₆O₂ 
• 355006-70-1 1-(4-chlorobenzoyl)-4,4-dimethoxy-3-fluoropiperidine 
• 355006-67-6 C₁₂H₁₁ClFNO₂ 

Relevant articles and documents

Subsitituted 1,4,8- triazaspiro [4,5]decan-2-one compounds

Novel 1,4,8-triazaspiro[4,5]decan-2-one compounds corresponding to formula I processes for the preparation thereof, related methods of treatment and pharmaceutical formulations containing such compounds.

SUBSTITUTED 1,4,8-TRIAZASPIRO[4,5]DECAN-2-ON COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY

The invention relates to the substituted 1,4,8-triazaspiro[4.5]decan-2-on compounds of formula (I), to methods for producing the same, to drugs containing said compounds and to the use of said compounds for producing drugs.

Arylidene-1-azacycloalkanes and arylalkyl-1-azacyclo-alkanes, their salts, medicaments containing these compounds and their use, and processes for their preparation

The invention relates to arylidene-1-azacycloalkanes and arylalkyl-1-azacycloalkanes of the general formula STR1 (wherein n, m, p, A, W1, W2, X, Y, and R1 to R11 are as defined in claim 1) and the isomers, isomer mixtures and salts thereof, which have useful properties, in particular an inhibitory effect on cholesterol biosynthesis.