153815-60-2

Usage

Uses

Used in Biochemistry Research:
FMOC-L-TRYPTOPHANOL is used as a reagent for peptide synthesis, facilitating the Fmoc protection method to prevent side reactions during the synthesis process.
Used in Pharmaceutical Development:
FMOC-L-TRYPTOPHANOL is used as a building block in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and therapeutics.
Used in Laboratory Settings:
FMOC-L-TRYPTOPHANOL is used as a research tool in laboratories, where its light sensitivity and complex structure are carefully managed to ensure its effectiveness in experiments and analyses.

Upstream product

• 102774-86-7 9-fluorenylmethyl N-succinimidyl carbonate 
• 154-09-6 L-tryptophanol 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 

Downstream Products

• 886991-16-8 C₄₀H₆₁N₃O₅SSi 
• 851707-51-2 tert-butyl (S)-3-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropyl)-1H-indole-1-carboxylate 

Relevant academic research and scientific papers

Design, synthesis, and immunochemical characterization of a chimeric glycopeptide corresponding to the Shigella flexneri Y O-polysaccharide and its peptide mimic MDWNMHAA

Two glycopeptide chimeras corresponding to the Shigella flexneri Y O-polysaccharide and its peptide mimic were designed in an attempt to improve the binding affinity by increasing the entropy of binding relative to the original octapeptide mimic of the O-

Asymmetric synthesis of highly substituted azapolycyclic compounds via 2-alkenyl sulfoximines: Potential scaffolds for peptide mimetics

The application of metalated, enantiomerically pure acyclic and cyclic 2-alkenyl sulfoximines for the synthesis of highly substituted aza(poly)cyclic ring systems is described. The method relies on a one-pot combination of a reagent-controlled allyl transfer reaction to α- or β-amino aldehydes, followed by a Michael-type cyclization of the intermediate vinyl sulfoximines generated in the first step. The sulfur-free target compounds are preferentially obtained by samarium iodide treatment of the sulfonimidoyl substituted heterocycles. In addition to this methodological work, initial results on the biological activity of selected examples are reported. Furthermore, a concept for the transformation of peptidic lead structures into non-peptide mimetics is described, and the relevance of the new approach to highly substituted azaheterocycles in this context is discussed.

Synthesis of Chiral N-Protected β-Amino Alcohols by the Use of UNCAs

A facile synthesis of a wide variety of N-protected β-amino alcohol derivatives under mild conditions is described.N-urethane protected amino acid N-carboxyanhydrides (UNCAs) were used as starting material and reduced into the corresponding alcohols with