15875-54-4

Basic information

• Product Name: 2-((4-CHLOROPHENYL)METHYLENE)INDANE-1,3-DIONE
• Synonyms: ASISCHEM Z66941;AKOS BBS-00005704;2-[(4-CHLOROPHENYL)METHYLENE]-1H-INDENE-1,3(2H)-DIONE;2-((4-CHLOROPHENYL)METHYLENE)INDANE-1,3-DIONE
• CAS NO: 15875-54-4
• Molecular Formula: C₁₆H₉ClO₂
• Molecular Weight: 268.69
• Mol File: 15875-54-4.mol
• Article Data: 35

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-((4-CHLOROPHENYL)METHYLENE)INDANE-1,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4-CHLOROPHENYL)METHYLENE)INDANE-1,3-DIONE(15875-54-4)
• EPA Substance Registry System: 2-((4-CHLOROPHENYL)METHYLENE)INDANE-1,3-DIONE(15875-54-4)

Safety Data

• Hazardous Substances Data: 15875-54-4(Hazardous Substances Data)

Usage

Chemical class

Indane-1,3-diones

Physical appearance

Yellow crystalline solid

Usage

Organic synthesis, pharmaceutical research, potential drug development

Pharmacological properties

Anti-inflammatory, potential anticancer activities

Biological activities

Interactions with biological systems due to the presence of a 4-chlorophenyl group

Target for investigation

Drug discovery and development

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 91446-49-0 sodium 2-(ethoxycarbonyl)-1-oxo-1H-inden-3-olate 
• 1088-36-4 2-<4-Chlor-benzyl>-indandion-(1,3) 
• 606-23-5 1H-indene-1,3(2H)-dione 
• 27402-31-9 5-(4-chlorobenzylidene)barbituric acid 
• 84-66-2 Diethyl phthalate 
• 109520-78-7 2-(4-chlorophenyl)-1,1,-dinitroethene 
• 2362-79-0 N-(4-chlorobenzylidene)aniline 

Downstream Products

• 127871-14-1 2-[4-(4-Chloro-phenyl)-3-cyano-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridin-2-ylsulfanyl]-acetamide 
• 127871-03-8 2-[(4S,4aR)-3-Cyano-9b-hydroxy-4-(4-nitro-phenyl)-5-oxo-4,4a,5,9b-tetrahydro-1H-indeno[1,2-b]pyridin-2-ylsulfanyl]-acetamide 
• 118373-55-0 C₂₂H₁₁ClN₄O₂ 
• 103966-50-3 2-[1-(4-Chloro-phenyl)-3-oxo-3-phenyl-propylidene]-indan-1,3-dione 
• 122631-67-8 3-(4-Chloro-phenyl)-3,3a-dihydro-2H-indeno[1,2-c]pyrazol-4-one 
• 122631-63-4 2-Bromo-2-[bromo-(4-chloro-phenyl)-methyl]-indan-1,3-dione 
• 82607-22-5 4-(4-Chloro-phenyl)-3-phenyl-3,4-dihydro-1H-indeno[1,2-b]pyridine-2,5-dione 
• 127322-76-3 3'-(4-chlorophenyl)spiro[2H-indene-2,2'-oxirane]-1,3-dione 
• 1600516-58-2 2-(4-chlorophenyl)-4H-indeno[2,1-d][1,3]oxazol-4-one 
• 1600516-56-0 dimethyl 5'-(4-chlorophenyl)-1,3-dioxo-1'-phthalimido-1,1',3,5'-tetrahydrospiro[indene-2,2'-pyrrole]-3',4'-dicarboxylate 

Relevant articles and documents

Leishmanicidal and cytotoxic activities and 4D-QSAR of 2-arylidene indan-1,3-diones

The indan-1,3-dione and its derivatives are important building blocks in organic synthesis and present important biological activities. Herein, the leishmanicidal and cytotoxicity evaluation of 16 2-arylidene indan-1,3-diones is described. The compounds w

Synthesis of novel spiro-tetrahydroquinoline derivatives and evaluation of their pharmacological effects on wound healing

A highly diastereoselective method for the synthesis of novel spiro-tetrahydroquinoline derivatives is reported here, using a one-pot reaction method. All compounds were characterized by1 H-nuclear magnetic resonance (NMR) and mass spectroscopy

Phosphine-Catalyzed Cascade Michael Addition/[4+2] Cycloaddition Reaction of Allenoates and 2-Arylidene-1,3-indanediones

The phosphine-catalyzed cascade Michael addition/[4+2] cycloaddition reaction of tetrahydrobenzofuranone-derived allenoates and 2-arylidene-1,3-indanediones has been reported, affording spirocyclic 1,3-indanedione derivatives in moderate to high yields wi