169287-77-8

Basic information

• Product Name: BOC-PNA-G(Z)-OH
• Synonyms: (BOC-G(Z)-AEG-OH)
• CAS NO: 169287-77-8
• Molecular Formula: C₂₄H₂₉N₇O₈
• Molecular Weight: 543.52916
• Mol File: 169287-77-8.mol

Chemical Properties

• Appearance: /
• Density: 1.44±0.1 g/cm3(Predicted)
• PKA: 3.32±0.10(Predicted)
• CAS DataBase Reference: BOC-PNA-G(Z)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-PNA-G(Z)-OH(169287-77-8)
• EPA Substance Registry System: BOC-PNA-G(Z)-OH(169287-77-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 169287-77-8(Hazardous Substances Data)

Usage

Uses

Used in Nucleic Acid Research:
BOC-PNA-G(Z)-OH is used as a research tool for studying the interactions between PNA and nucleic acids, such as DNA and RNA, due to its high binding affinity and specificity.
Used in Diagnostics:
In the diagnostics industry, BOC-PNA-G(Z)-OH is used as a molecular probe for detecting specific DNA or RNA sequences, contributing to the development of sensitive and accurate diagnostic assays.
Used in Therapeutics:
BOC-PNA-G(Z)-OH is utilized as a building block in the development of antisense oligonucleotides, which have potential therapeutic applications in modulating gene expression and treating various diseases by targeting specific nucleic acid sequences.
Used in Drug Development:
In the pharmaceutical industry, BOC-PNA-G(Z)-OH is used as a component in the design of drugs that target specific genetic sequences, potentially leading to more targeted and effective treatments for a range of conditions.

Upstream product

• 406683-60-1 (E)-17-[N-[2-(tert-Butyloxycarbonylamino)ethyl]-N-fluorenylmethyloxycarbonylglycinyloxy]-4,7,10,13-tetraoxa-15-heptadecenoic acid phenacyl ester 
• 141743-15-9 2-((((9H-fluoren-9-yl)methoxy)carbonyl)(2-((tert-butoxycarbonyl)amino)ethyl)amino)acetic acid 
• 72648-80-7 ethyl 2-[2-(tert-butoxycarbonylamino)ethyl-[3-[[4-(4,5-difluoro-2-methylsulfanyl-phenyl)phenoxy]methyl]benzoyl]amino]acetate 
• 90495-99-1 N-(2-tert-butoxycarbonylaminoethyl)aminoacetic acid 
• 169287-69-8 2-[2-(benzyloxycarbonyl)amino-6-oxo-1,6-dihydro-9H-purin-9-yl]acetic acid 
• 230618-02-7 (E)-17-[N-[2-(tert-Butyloxycarbonylamino)ethyl]-N-fluorenylmethyloxycarbonylglycinyloxy]-4,7,10,13-tetraoxa-15-heptadecenoic acid 

Downstream Products

• 1009310-78-4 C₅₆H₇₄N₁₆O₁₄ 
• 1009310-79-5 C₅₈H₇₈N₁₆O₁₄ 
• 249287-96-5 N-[2-(N-dithiasuccinoyl)aminoethyl]-N-[[2-N-(benzyloxycarbonyl)guanin-9-yl]acetyl]glycine 
• 230618-01-6 C₆₃H₇₀N₂₀O₁₉ 

Relevant articles and documents

A convergent strategy for the modification of peptide nucleic acids: Novel mismatch-specific PNA-hybridization probes

Coupling of nonnatural nucleobases to the orthogonally protected backbone 1 on the solid phase provided access to novel peptide nucleic acid (PNA) conjugates 2, which are difficult to synthesize by standard routes. Hybridization probes containing the thia

Convergent strategies for the attachment of fluorescing reporter groups to peptide nucleic acids in solution and on solid phase

The site-selective conjugation of peptide nucleic acids (PNA) with fluorescent reporter groups is essential for the construction of hybridisation probes that can report the presence of a particular DNA sequence. This paper describes convergent methods for