406683-60-1Relevant academic research and scientific papers
Convergent strategies for the attachment of fluorescing reporter groups to peptide nucleic acids in solution and on solid phase
Seitz, Oliver,Koehler, Olaf
, p. 3911 - 3925 (2007/10/03)
The site-selective conjugation of peptide nucleic acids (PNA) with fluorescent reporter groups is essential for the construction of hybridisation probes that can report the presence of a particular DNA sequence. This paper describes convergent methods for
A convergent strategy for the modification of peptide nucleic acids: Novel mismatch-specific PNA-hybridization probes
Seitz, Oliver,Bergmann, Frank,Heindl, Dieter
, p. 2203 - 2206 (2007/10/03)
Coupling of nonnatural nucleobases to the orthogonally protected backbone 1 on the solid phase provided access to novel peptide nucleic acid (PNA) conjugates 2, which are difficult to synthesize by standard routes. Hybridization probes containing the thia
