170649-26-0Relevant articles and documents
Total synthesis of virgatolide B
Hume, Paul A.,Furkert, Daniel P.,Brimble, Margaret A.
supporting information, p. 4588 - 4591 (2013/09/24)
The first total synthesis of the benzannulated spiroketal virgatolide A is presented. Key features include sp3-sp2 Suzuki coupling of an enantiomerically enriched β-trifluoroboratoamide and an aryl bromide, regioselective intramolecular carboalkoxylation, and a 1,3-anti-selective Mukaiyama aldol reaction followed by global deprotection/cyclization with regioselectivity governed by internal hydrogen bonding.
An efficient method for the p-methoxybenzylation of hydroxy groups with 2-(4-methoxybenzyloxy)-3-nitropyridine
Nakano, Masakazu,Kikuchi, Wataru,Matsuo, Jun-Ichi,Mukaiyama, Teruaki
, p. 424 - 425 (2007/10/03)
2-(4-Methoxybenzyloxy)-3-nitropyridine (PMBONPy), easily prepared from 2-chloro-3-nitropyridine and p-methoxybenzyl (PMB) alcohol, reacts with various types of hydroxy groups in the presence of a catalytic amount of trimethylsilyl triflate (Me3SiOTf) to give the corresponding PMB ethers in high yields under mild conditions.
An Efficient Synthesis of Radicinin Analogues
Eh, Marcus,Schomburg, Dietmar,Schicht, Kathrin,Kalesse, Markus
, p. 8983 - 8992 (2007/10/02)
We described herein an enantio- and diastereoselective total synthesis of two radicinin analogues 13 and 14. 13 has been subjected to biological tests, exhibiting the lowest toxicity of all radicinin analogues that have been investigated to date and it de
