170749-59-4

Basic information

• Product Name: 3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate
• Synonyms: 3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate;3-Amino-3-iminopropanoic acid;1-Benzidlilazetidin-3-yl-3-aMino-3-iMinopropanoate Monoacetate;2-carbaMiMidoylacetic acid;1-(diphenylmethyl)azetidin-3-yl 2-carbamimidoylacetate;1-(diphenylmethyl)azetidin-3-yl 2-carbamimidoylacetate acetate;azetidinyl ester Monoacetate;3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate 3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate
• CAS NO: 170749-59-4
• Molecular Formula: C21H25N3O4
• Molecular Weight: 383.44
• EINECS: 1592732-453-0
• Mol File: 170749-59-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate(170749-59-4)
• EPA Substance Registry System: 3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate(170749-59-4)

Safety Data

• Hazardous Substances Data: 170749-59-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate is used as a key building block for the synthesis of various drugs and compounds. Its unique properties and structure contribute to the development of innovative and effective medications, playing a significant role in advancing pharmaceutical research and treatment options.
Used in Research and Development:
In the realm of research and development, 3-Amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate is utilized for its versatile nature and adaptability. It is employed in the creation of new treatments for a range of medical conditions, with its potential applications spanning across different industries due to its ability to be modified for specific purposes.

InChI:InChI=1/C19H21N3O2.C2H4O2/c20-17(21)11-18(23)24-16-12-22(13-16)19(14-7-3-1-4-8-14)15-9-5-2-6-10-15;1-2(3)4/h1-10,16,19H,11-13H2,(H3,20,21);1H3,(H,3,4)

Upstream product

• 631-61-8 ammonium acetate 
• 116574-14-2 1-benzhydrylazetidin-3-yl cyanoacetate 

Relevant articles and documents

Azelnidipine preparation method (by machine translation)

The invention relates to a blood pressure lowering medicine azhediping preparation method, which belongs to the field of medicine. The method of the traditional synthetic route trunk compound 4 of the improved synthetic conditions, of the original anhydrous reaction conditions is changed into the water under the conditions of the reaction, not only is easy to operate, but also to reduce the requirement of anhydrous reaction solvent, thus very suitable for industrial production. (by machine translation)

Novel 2-amino-1,4-dihydropyridine calcium antagonists. II. Synthesis and antihypertensive effects of 2-amino-1,4-dihydropyridine derivatives having N,N-dialkylaminoalkoxycarbonyl groups at 3- and/or 5-positions

Novel 2-amino-1,4-dihydropyridine derivatives I, which contain N,N-dialkylaminoalkoxycarbonyl groups at the 3- and/or 5-position, were synthesized and their antihypertensive effects were evaluated in spontaneously hypertensive rats. Remarkably prolonged duration of antihypertensive action was observed when a tertiary amino group was introduced into either the 3- or 5-ester side-chain of the 1,4-dihydropyridine ring. In particular, the compounds containing cyclic amino moieties at the 3-position showed greater potency than those with acyclic amino moieties. Chemical modification studies indicated that the two ester side-chains of 1,4-dihydropyridine at the 3- and 5-position might function in a different manner in relation to the antihypertensive activities. 3-(1-Benzhydrylazetidin-3-yl) 5-isopropyl 2-amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxyl ate, I-43 (CS-905), exhibited potent and long-lasting antihypertensive effects with gradual onset of action, and is a promising candidate as an antihypertensive drug.